首页> 外国专利> COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING MULTIPLE ORGAN DYSFUNCTION SYNDROME

COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING MULTIPLE ORGAN DYSFUNCTION SYNDROME

机译:用于治疗或预防多器官功能障碍综合征的组合物和方法

摘要

A PN composition for treating multiple organ dysfunction syndrome (MODS) comprises a lipophilic or hydrophobic component, an amphiphilic emulsifier, a polar liquid carrier, and one or more electrolytes, where the amphiphilic emulsifier forms micelles having a lipophilic or hydrophobic core comprising the lipophilic or hydrophobic component in the polar liquid carrier, and /or liposomes organized as a lipid bilayer and/or other particle configurations. This is a PN composition that takes up nitric oxide and releases it with enhanced rapidity enabling it to shift the balance of nitric oxide from one that exacerbates organ damage and decreased survivability to one that reverses and/or inhibits organ damage and increases survivability.
机译:用于处理多器官功能障碍综合征(MODS)的PN组合物包含亲脂或疏水组分,两亲乳化剂,极性液体载体和一种或多种电解质,其中两亲乳化剂形成具有脂质或疏水核心的胶束,其包含亲脂或疏水核心 极性液体载体中的疏水成分,和/或组织为脂质双层和/或其他颗粒构型的脂质体。 这是一种PN组合物,其占用一氧化氮并释放它,并通过增强的快速释放,使其能够将一氧化氮的平衡从加剧器官损伤加剧并降低到逆转和/或抑制器官损伤的情况下减少并提高生存性。

著录项

  • 公开/公告号WO2021203143A1

    专利类型

  • 公开/公告日2021-10-07

    原文格式PDF

  • 申请/专利权人 VIVACELLE BIO INC.;

    申请/专利号WO2021US70351

  • 发明设计人 SIMPKINS CUTHBERT;

    申请日2021-04-02

  • 分类号A61P43;A61K9/127;A61K9;A61K47/02;

  • 国家 US

  • 入库时间 2022-08-24 21:33:06

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号