首页> 外国专利> PHARMACEUTICAL SUMMARY, STRENGTHS OF THE MEDICINAL PRODUCTS, ROUTE OF ADMINISTRATION AND ROUTE OF ADMINISTRATION

PHARMACEUTICAL SUMMARY, STRENGTHS OF THE MEDICINAL PRODUCTS, ROUTE OF ADMINISTRATION AND ROUTE OF ADMINISTRATION

机译:药品摘要,药品优势,行政管理和行政途径

摘要

The present invention provides a pharmaceutical composition, a patch and a manufacturing method thereof, an analgesic method, and an application. The pharmaceutical composition comprises a single anesthetic active ingredient. The anesthetic active ingredient comprises a water-dissolving anesthetic active ingredient and an anesthetic active ingredient existing in an insoluble form. The mass percent content of the anesthetic active ingredient in the pharmaceutical composition is 2% or more. The mass percent content of the water-dissolving anesthetic active ingredient in the pharmaceutical composition is 1% or less. The anesthetic active ingredient comprises lidocaine, tetracaine, bupivacaine, articaine, cinchocaine, dibucaine, etidocaine, levobupivacaine, mepivacaine, prilocaine, ropivacaine, trimecaine, benzocaine or procaine. The pharmaceutical composition and the patch can provide continuous analgesia for 12-30 hours. The patch is resistant to a certain amount of external squeezing force, preventing a formulation layer covered by the same from being squeezed out, thereby maintaining the thickness of the formulation layer.
机译:本发明提供了药物组合物,贴剂及其制造方法,镇痛方法和应用。药物组合物包含单一麻醉活性成分。麻醉活性成分包括水溶性麻醉活性成分和存在于不溶性形式的麻醉活性成分。药物组合物中麻醉活性成分的质量百分比为2%以上。药物组合物中水溶性麻醉活性成分的质量%含量为1%或更少。麻醉活性成分包括利多卡因,四鲸,布奈卡因,牙科蛋白酶,矿物,Dibucapee,Etidocaine,左撇子,梅特卡卡因,胰岛素,罗哌港,血清素,苯陶器或促进。药物组合物和贴剂可以提供连续的镇痛12-30小时。贴片耐含有一定量的外部挤压力,防止由挤出的相同覆盖的配方层,从而保持配方层的厚度。

著录项

  • 公开/公告号EP3741364A4

    专利类型

  • 公开/公告日2021-10-27

    原文格式PDF

  • 申请/专利权人 ZHANG JIE;

    申请/专利号EP20190741485

  • 发明设计人 ZHANG JIE;

    申请日2019-01-16

  • 分类号A61K31/167;A61K9/70;A61K31/245;A61K31/445;A61K45;A61K47/32;A61P23/02;

  • 国家 EP

  • 入库时间 2022-08-24 21:56:19

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