首页> 外国专利> HUMAN ANTIBODY AND FRAGMENTS THEREOF FOR USE IN THE TREATMENT OF GASTRIC CANCER (GC) AND OTHER TYPES OF TUMOURS EXPRESSING THE MICA PROTEIN (MHC CLASS I CHAIN-RELATED PROTEIN A GENE)

HUMAN ANTIBODY AND FRAGMENTS THEREOF FOR USE IN THE TREATMENT OF GASTRIC CANCER (GC) AND OTHER TYPES OF TUMOURS EXPRESSING THE MICA PROTEIN (MHC CLASS I CHAIN-RELATED PROTEIN A GENE)

机译：用于治疗胃癌（GC）和其他类型的表达云母蛋白的肿瘤的人类抗体和片段（MHC I类链条相关蛋白A基因）

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摘要

The present invention relates to fully human bivalent monoclonal antibody that specifically binds to the α1 subunit of MICA, SEQ ID NO: 1, CHARACTERIZED in that said antibody comprises a heavy chain variable domain of SEQ ID NO: 2 and a light chain variable domain of SEQ ID NO: 3.

机译：本发明涉及完全与云母，SEQ ID NO：1的α1亚基特异性结合的全人二价单克隆抗体，其特征在于，所述抗体包含SEQ ID NO：2的重链可变结构域和轻链可变结构域 SEQ ID NO：3。

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公开/公告号EP3744737A4

专利类型
公开/公告日2021-09-01

原文格式PDF
申请/专利权人 UNIVERSIDAD DE CHILE;
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申请/专利号EP20180894287
发明设计人 MOLINA SAMPAYO MARÍA CARMEN;AGUILLÓN GUTIERREZ JUAN CARLOS;HAGER RIBEIRO CAROLINA;ZÚÑIGA OLATE ROBERTO AQUILES;COLLAZO MUÑOZ NORBERTO ANDRÉS;LEIVA ARAYA LORENZO EUGENIO;GUTIERREZ GONZALEZ MATÍAS FERNANDO;TENEB LOBOS JAIME CAMILO;ROMERO TRUJILLO ALFONSO ENRIQUE;JEREZ DONOSO BASTIÁN NICOLÁS;
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申请日2018-12-27
分类号C07K16/30;A61K39;A61K39/395;A61P35;C07K16/18;C07K16/28;G01N33/574;
国家 EP
入库时间 2022-08-24 22:23:06

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