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ANALYSIS OF HLA ALLELIES IN TUMORS AND ITS APPLICATION
ANALYSIS OF HLA ALLELIES IN TUMORS AND ITS APPLICATION
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机译:肿瘤中HLA等位基因分析及其应用
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摘要
The present invention relates to a method for determining whether an HLA allele is lost in a tumour in a subject, wherein said method comprises the step of determining the specific copy number of said HLA allele in said tumour. The invention also relates to a method for treating cancer in a subject, comprising targeting a neoantigen which is predicted to be presented by an HLA molecule encoded by an HLA allele which has been determined not to have been lost in a tumour in said subject.
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