METHOD AND APPARATUS FOR PROVIDING MATHMATICS TUTORING CONTENTS TRHOUGH REPETITIVE LEARNING

• 1. 用于基于学习效率提供私人定制教育内容的机械学习方法、装置及计算机程序 [P] . 中国专利： CN111328407A . 2020-06-23
• 2. 利用二进制原理的学习内容提供装置及其方法 [P] . 中国专利： CN110506290A . 2019-11-26
• 3. APPARATUS AND METHOD FOR PROVIDING KOREAN LANGUAGE TUTORING CONTENTS TRHOUGH REPETITIVE LEARNING [P] . KR102248932B1 . 2021-05-04

  机译： 通过重复学习提供韩语辅导内容的装置和方法

• 4. APPARATUS AND METHOD FOR PROVIDING CHINESE TUTORING CONTENTS TRHOUGH REPETITIVE LEARNING [P] . KR102288531B1 . 2021-08-09

  机译： 通过重复学习提供中国辅导内容的装置和方法

• 5. APPARATUS AND METHOD FOR PROVIDING KOREAN HISTORY TUTORING CONTENTS TRHOUGH REPETITIVE LEARNING [P] . KR102297754B1 . 2021-09-02

  机译： 通过重复学习提供韩国历史辅导内容的装置和方法

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• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
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• 4. Survey of Prevalence and Risk Factors Associated with Upper Extremity Musculoskeletal Disorders by Repetitive Job Activities Methods in Baker of Iran [J] . Morteza Mortazavi Mehrizi ,Mehrzad Ebrahemzadih ,Abdolhamid Tajvar . 健康（英文） . 2014,第21期
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