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Food composition for preventing or improving obesity or fatty liver disease comprising a new Pediococcus pentosaceus strain and its whey fermentation product

机译:用于预防或改善肥胖或脂肪肝疾病的食物组合物,所述肥胖或脂肪肝疾病包括新的Pediococcus戊段菌株及其乳清发酵产物

摘要

The present invention relates to a Pediococcus pentosaceus KI13 strain of accession number KACC 81116BP that exhibits anti-obesity activity during whey fermentation, obesity or fatty liver disease comprising a whey fermented product bioconverted to the strain It relates to a food composition for prevention or improvement, a food additive composition, and a pharmaceutical composition. In the present invention, the whey ferment bioconverted to the P. pentosaceus KI13 strain reduces the weight gain by inhibiting pancreatic lipase activity, inhibiting α-amylase and α-glucosidase activity, and inhibiting differentiation of mast cells, and By reducing the expression of genes and proteins related to obesity and inflammation in adipose tissue, it is characterized in that it exhibits a preventive, ameliorating or therapeutic effect on obesity and fatty liver disease.
机译:本发明涉及PETOCCCUS戊烃KI13菌株的加入数KACC 81116BP,其在乳清发酵期间表现出抗肥胖活性,所述乳清液或脂肪肝病,所述乳清肝疾病所述乳清发酵产物所述生物转化为所述菌株,其涉及用于预防或改进的食品组合物, 食品添加剂组合物和药物组合物。 在本发明中,生物蒙粥末端的乳清发酵术通过抑制胰脂肪酶活性,抑制α-淀粉酶和α-葡糖苷酶活性,抑制肥大细胞的分化,以及减少基因的表达来降低重量增益,并通过降低基因的表达 和脂肪组织中肥胖和炎症有关的蛋白质,其特征在于它表现出对肥胖和脂肪肝疾病的预防,改善或治疗作用。

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