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METHODS OF TREATING CERVICAL CANCER BY ADMINISTERING THE PD-1 INHIBITOR ANTIBODY CEMIPLIMAB

机译:通过施用PD-1抑制剂抗体CeMimpimab治疗宫颈癌的方法

摘要

The present disclosure provides methods for treating, reducing the severity of, or inhibiting the growth of a tumor or improving overall survival in a cervical cancer patient, wherein the method includes selecting a patient with cervical cancer in need thereof and administering to the patient a therapeutically effective amount of a programmed death 1 (PD-1) inhibitor (e.g., an anti-PD-1 antibody or antigen-binding fragment thereof such as cemiplimab or a bioequivalent thereof). In certain embodiments, the patient has recurrent or metastatic cervical cancer with disease progression on or after chemotherapy.
机译:本公开提供了治疗,减少肿瘤的严重程度或改善宫颈癌患者的肿瘤生长或改善整体存活的方法,其中该方法包括选择有需要的宫颈癌并给予患者治疗患者 有效量的编程死亡1(PD-1)抑制剂(例如,抗PD-1抗体或其抗原结合片段,例如Cemizlimab或其生物等值)。 在某些实施方案中,患者在化疗中或之后具有疾病进展的复发或转移性宫颈癌。

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