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Diacyland arylheteroaryl urea derivatives as modulators of 5-HT2A serotonin receptors useful for prevention and treatment of hallucinosis associated with neurodegenerative diseases and their derivatives

机译：二甘蓝芳基代芳亚芳脲尿素衍生物作为5-HT2A血清素受体的调节剂，可用于预防和治疗与神经变性疾病及其衍生物相关的幻觉病症

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摘要

Problem to be solved: to provide a diasterine and arylheteroaryl urea derivatives as modulators of 5-HT2A serotonin receptors useful for prevention and treatment of hallucinosis associated with neurodegenerative diseases.Solution 5 provides the use of a specific pyrazole derivative of the formula (I) modulating the activity of the 5-HT2A serotonin receptor and its use for treating and preventing hallucinosis associated with Lewy body type dementia.Diagram

机译：要解决的问题：提供一种用于预防和治疗与神经变性疾病相关的5-HT2A血清素受体的调节剂作为5-HT2A血清蛋白受体的调节剂。溶解5提供了式（I）的特定吡唑衍生物的用途 5-HT2A血清素受体的活性及其用于治疗和预防与Lewy体型Dememia.diagrang的幻蛋病

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公开/公告号JP2021185144A

专利类型
公开/公告日2021-12-09

原文格式PDF
申请/专利权人アクソヴァントサイエンシーズゲゼルシャフトミットベシュレンクテルハフツング;フリードホフ;ローレンスティム;ラマスワミー;シャンカー;ウェン;イェンドン;
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申请/专利号JP20210125769
发明设计人フリードホフ;ローレンスティム;ラマスワミー;シャンカー;ウェン;イェンドン;
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申请日2021-07-30
分类号A61K31/415;A61K31/135;A61K31/445;A61K31/4468;A61K31/496;A61K31/517;A61K31/519;A61K31/5513;A61K45;A61K45/06;A61P25;A61P25/16;A61P25/18;A61P25/20;A61P25/28;A61P43;
国家 JP
入库时间 2022-08-24 22:44:28

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