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IMMUNOLOGICAL COMPOSITION FOR DIAGNOSIS OF LUNG CANCER BY USING AUTOANTIBODY-ANTIGEN COMPLEX, DIAGNOSIS METHOD FOR LUNG CANCER BY USING SAME, AND LUNG CANCER DIAGNOSIS KIT COMPRISING SAME
IMMUNOLOGICAL COMPOSITION FOR DIAGNOSIS OF LUNG CANCER BY USING AUTOANTIBODY-ANTIGEN COMPLEX, DIAGNOSIS METHOD FOR LUNG CANCER BY USING SAME, AND LUNG CANCER DIAGNOSIS KIT COMPRISING SAME
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机译:通过使用同一肺癌诊断方法的肺癌诊断免疫组合物,其相同,肺癌诊断试剂盒
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摘要
The present disclosure provides an immunological composition for diagnosing lung cancer comprising: an antibody composition A containing an anti-CYFRA21-1 primary antibody-gene and an anti-CYFRA21-1 secondary antibody-detection marker; and an antibody composition B containing an anti-CYFRA 21-1 primary antibody-gene and an anti-human IgG antibody-detection marker; a method for diagnosing lung cancer in a human biological specimen using the same, and a diagnostic kit for lung cancer using the same.;The composition for diagnosing lung cancer and the diagnostic method for lung cancer according to the present disclosure can diagnose the onset of lung cancer stages 0 to IV in a non-invasive biological specimen with a specificity of 90% or more and a sensitivity of 75% or more. In particular, since an autoantibody whose concentration increases rapidly in the early stage of lung cancer is used, it is possible to diagnose the onset of lung cancer stages 0 to 1 with a sensitivity of 76% or more.
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