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Simulation method of closed spleen injury in large-scale experimental animal experiment

机译:大型实验动物实验中脾损伤的仿真方法

摘要

FIELD: experimental medicine.;SUBSTANCE: invention relates to experimental medicine, namely to pathological physiology. The spleen is mobilized. Along the midaxillary line in the projection of the spleen, laparocentesis is performed using a trocar, through which a silicone tube is passed with an air balloon attached at the end, so that the air balloon is placed in the left hypochondrium between the spleen and the costal frame. Apply a bandage to the lower half of the abdomen. The animal is placed on its left side. The gas mixture is pumped into the balloon through the tube to inflate the balloon to rupture. In this case, either the stomach is filled with water through a gastric tube, or the chest of the animal is squeezed using weights of the required mass or manual reception when the animal is on the left side.;EFFECT: method allows to create a model corresponding to the mechanogenesis of a closed abdominal trauma; to create the same force and direction of action on the spleen for the reproducibility of the model; provides the ability to regulate the strength of the impact and visual control over the result of the impact; the absence of a general traumatic effect, influencing the course of a traumatic disease of an animal in order to avoid obtaining a false resu no pain in the postoperative period.;1 cl, 7 dwg, 1 ex
机译:现场:实验医学。物质:发明涉及实验医学,即病理生理学。脾脏被调动。沿着脾脏突出的血脂线,使用套管针进的泪穿刺件,通过该套管针进的是,硅树脂管通过附接到端的气球,使得空气球囊被放置在脾脏之间的左下丘脑中。肋架。将绷带涂抹在腹部下半部分。将动物放在左侧。将气体混合物通过管泵入球囊中以使气球膨胀破裂。在这种情况下,胃通过胃管填充水,或者当动物在左侧时,使用所需质量或手动接收的重量挤压动物的胸部。;效果:方法允许创建一个对应于闭孔腹腔创伤的机械手机的模型;为模型的再现性创造与脾脏上相同的力量和行动方向;提供对影响结果调节影响力和视觉控制的能力;没有一般的创伤效果,影响动物的创伤病变,以避免获得假结果;术后期间没有痛苦。; 1 cl,7 dwg,1例

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