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CHEMICALS AND METHODS TO PREVENT AND TREAT TGF-BETA MEDIATED ACTIVATION OF FIBROBLASTS TO REDUCE AND TREAT CANCER AND FIBROSIS
CHEMICALS AND METHODS TO PREVENT AND TREAT TGF-BETA MEDIATED ACTIVATION OF FIBROBLASTS TO REDUCE AND TREAT CANCER AND FIBROSIS
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机译：预防和治疗TGF-β的化学品和方法介导的成纤维细胞活化以减少和治疗癌症和纤维化
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摘要
A pharmaceutical composition for use in a method of treating an activated fibroblast associated disease or pre-disease condition in a mammal, the method comprising:administering the pharmaceutical composition including a therapeutically effective amount of a first therapeutic;wherein the first therapeutic is a YAP / TAZ inhibitor, or pharmacologically acceptable salts, solvates, esters, amides, clathrates, stereoisomers, enantiomers, prodrugs or analogs thereof, or a combination thereof.
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