首页> 外国专利> FUNCTIONAL COMPOSITION CONTAINING IMMORTALIZED STEM CELL-DERIVED EXOSOME-RICH CULTURE MEDIUM AND ROSEBUD EXTRACT AS ACTIVE INGREDIENTS

FUNCTIONAL COMPOSITION CONTAINING IMMORTALIZED STEM CELL-DERIVED EXOSOME-RICH CULTURE MEDIUM AND ROSEBUD EXTRACT AS ACTIVE INGREDIENTS

机译：含有永生化干细胞衍生的外渗培养基和玫瑰花蕾提取物作为活性成分的功能组合物

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摘要

The present disclosure relates to a functional composition containing an immortalized stem cell-derived exosome-rich conditioned medium and rosebud extract as active ingredients. Specifically, the composition containing the immortalized stem cell-derived exosome-rich conditioned medium and the rosebud extract as active ingredients, according to the present disclosure, has excellent activity in inhibiting mast cell granule secretion, inhibiting immunoglobulin E (IgE) in serum, inhibiting histamines in serum, and improving itchiness, and is excellent in tyrosinase inhibitory activity and melanin production inhibitory activity, and thus can be used in the manufacture of a cosmetic composition having activity in atopic dermatitis improvement, skin wrinkle improvement, and whitening as well as can be usefully used in the manufacture of a pharmaceutical composition for the prevention or treatment of atopic dermatitis and pigmentation diseases.

机译：本公开涉及含有永生化干细胞衍生的外渗条件培养基和玫瑰花蕾提取物作为活性成分的功能组合物。具体地，根据本发明的含有永生化干细胞衍生的外渗条件培养基和玫瑰花蕾提取物的组合物具有优异的活性，在抑制肥大细胞颗粒分泌，抑制血清中的免疫球蛋白E（IgE），抑制血清中的组胺，提高瘙痒，并且具有优异的酪氨酸酶抑制活性和黑色素产生抑制活性，因此可以用于制造具有在特应性皮炎的活性的化妆品组合物，皮肤皱纹改善和美白以及罐头有用品用于制造用于预防或治疗特应性皮炎和色素沉着疾病的药物组合物。

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公开/公告号EP3960154A1

专利类型
公开/公告日2022-03-02

原文格式PDF
申请/专利权人 CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION;DESIGNED CELLS CO. LTD.;
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申请/专利号EP20200794952
发明设计人 KIM YUN BAE;JEONG HEON SANG;CHOI EHN KYOUNG;
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申请日2020-04-17
分类号A61K8/98;A61K8/9789;A61Q19;A61Q19/08;A61Q19/02;A61K35/50;A61K36/73;A61P17;A23L33/10;A23L33/105;
国家 EP
入库时间 2022-08-24 23:41:34

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