首页> 外国专利> A method for producing a water-insoluble substance sample for MALDI mass spectrometry and a method for quantitative analysis of a water-insoluble substance using MALDI mass spectrometry.

A method for producing a water-insoluble substance sample for MALDI mass spectrometry and a method for quantitative analysis of a water-insoluble substance using MALDI mass spectrometry.

机译:一种用于产生用于MALDI质谱的水不溶性物质样品的方法,以及一种用于使用MALDI质谱对水不溶性物质进行定量分析的方法。

摘要

The present invention relates to a method for producing a sample having a uniform thickness of a homogeneous water-insoluble substance sample, and a method for quantitatively analyzing a water-insoluble substance by performing MALDI mass spectrometry on such a sample. is there. Specifically, the sample is obtained by adding a volatile solvent to a mixture of a water-insoluble substance and a matrix and dispersing the mixture of the water-insoluble substance and the matrix until the solvent evaporates. It can be manufactured by putting it in a pellet cup, pressing it at the same pressure, and then dissolving the pellet cup in water.
机译:本发明涉及一种制备具有均匀水不溶性物质样品的均匀厚度的样品的方法,以及一种通过对此类样品进行MALDI质谱分析来定量分析水不溶性物质的方法。有。具体而言,通过向水不溶性物质和基质的混合物中添加挥发性溶剂,并分散水不溶性物质和基质的混合物,直到溶剂蒸发,从而获得样品。它可以通过将其放入颗粒杯中,在相同压力下按压,然后将颗粒杯溶解在水中来制造。

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