首页> 外国专利> Octreotide Microsphere-Based Arterial Embolization for Treating Obesity

Octreotide Microsphere-Based Arterial Embolization for Treating Obesity

机译:奥曲肽微球动脉栓塞治疗肥胖

摘要

This invention provides a method for causing weight loss in a subject comprising introducing biodegradable microspheres into one or more of the subject's gastric arteries, wherein the microspheres (i) have a d90 value from 40 μm to 500 μm; (ii) comprise polylactic acid (PLA) and/or polylactic co-glycolic acid (PLGA); (iii) carry a therapeutically effective amount of pharmaceutical octreotide; (iv) embolize gastric arterial vessels supplied by the one or more arteries into which they are introduced; and (v) release octreotide during embolization.
机译:本发明提供了一种使受试者体重减轻的方法,包括将可生物降解微球引入受试者的一条或多条胃动脉,其中微球(i)的d90值为40μm至500μm;(ii)包含聚乳酸(PLA)和/或聚乳酸-共乙醇酸(PLGA);(iii)携带治疗有效量的药物奥曲肽;(iv)栓塞由一条或多条动脉供应的胃动脉血管;(v)栓塞期间释放奥曲肽。

著录项

  • 公开/公告号US2022088150A1

    专利类型

  • 公开/公告日2022-03-24

    原文格式PDF

  • 申请/专利权人 BIOVENA SCIENCE LLC;

    申请/专利号US201917277342

  • 发明设计人 FUAD NURILI;OMER ARAS;

    申请日2019-09-19

  • 分类号A61K38/31;A61K9/16;A61P3/04;A61L24/04;

  • 国家 US

  • 入库时间 2022-08-25 00:04:24

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