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Octreotide Microsphere-Based Arterial Embolization for Treating Obesity
Octreotide Microsphere-Based Arterial Embolization for Treating Obesity
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机译:奥曲肽微球动脉栓塞治疗肥胖
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摘要
This invention provides a method for causing weight loss in a subject comprising introducing biodegradable microspheres into one or more of the subject's gastric arteries, wherein the microspheres (i) have a d90 value from 40 μm to 500 μm; (ii) comprise polylactic acid (PLA) and/or polylactic co-glycolic acid (PLGA); (iii) carry a therapeutically effective amount of pharmaceutical octreotide; (iv) embolize gastric arterial vessels supplied by the one or more arteries into which they are introduced; and (v) release octreotide during embolization.
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