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首页> 外文会议>The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议）论文集 >Biomechanical study on the stability and Finite-element analysis of stress distribution in reconstructed pelvis with autograft after hindquarter amputation
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Biomechanical study on the stability and Finite-element analysis of stress distribution in reconstructed pelvis with autograft after hindquarter amputation

机译：后肢截肢后自体骨盆重建骨盆的应力分布稳定性和有限元分析的生物力学研究

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Background: Treatment of malignant tumors of the pelvis, especially in the periacetabular region continues to present one of the most challenging problems in oncological and orthopedic surgery. Even now, hindquarter amputation is still the only choice for some patients, but hindquarter amputation can cause much trouble in sitting, standing and in fitting the exoprosthesis of patients after amputation, and their quality of life and function were always poor. Method: The weight bearing function of pelvis with autograft was restored after hindquarter amputation on 10 cadaveric pelves along with the lumbar and bilateral lower limbs, analyzed the stability of reconstructed pelvis under the axial loading in gradient from 0-500N. The finite element model of the intact pelvis was constructed based on computed tomography (CT) images of the pelvis of a healthy 30-year-old man and investigate its stress distribution under physiological loading. Results: Biomechanical experiment showed that the intact pelvis was the most stable condition compared to the reconstructed models according to the capability of pelvis resisting compression in axial direction, but the intact pelvis and reconstructed models were restored anterior stateafter removed loading. There had no statistical difference in displacements of pelvis reconstructed by femur or tibia (p>0.05). The FEM analyses showed as following: the stress distribution in normal pelvis was symmetric and the concentration of stress located along ischio sacral arch. The maximum stress of the reconstructed pelvis was higher compared with that of intact pelvis. The stress distribution in two reconstructed pelves was similar. The maximum stress concentrated on the shaft of reconstructive tibia, which was less than that of reconstructive femur, in that the stress distribution was near screw. Conclusion: The stability of reconstructed pelvis is weaker than that of intact pelvis, but the stability of reconstructed pelvis is effective and it could bear human weight at earlier time. The maximum stress of the reconstructed pelvis is higher than that of intact pelvis and the reconstruction by femur is benefit for preventing bone fracture.
机译：背景：骨盆恶性肿瘤的治疗，尤其是在髋臼周围区域，一直是肿瘤和骨科手术中最具挑战性的问题之一。即使是现在，后肢截肢术仍然是某些患者的唯一选择，但是后肢截肢术会在截肢后患者的坐姿，站立姿势和适合他们的假体上造成很多麻烦，并且他们的生活质量和功能始终很差。方法：对10具尸体骨盆以及腰椎和双侧下肢进行后肢截肢后，恢复自体骨盆的负重功能，并分析在0-500N的梯度轴向载荷下重建骨盆的稳定性。基于健康的30岁男人的骨盆的计算机断层扫描（CT）图像，构建完整的骨盆的有限元模型，并研究其在生理负荷下的应力分布。结果：生物力学实验表明，根据骨盆抵抗轴向压缩的能力，与重建模型相比，完整的骨盆是最稳定的状态，但是在去除负荷后，完整的骨盆和重建的模型可以恢复到前状态。由股骨或胫骨重建的骨盆位移无统计学差异（p> 0.05）。有限元分析表明：正常骨盆的应力分布是对称的，应力集中在坐骨is骨弓上。与完整的骨盆相比，重建的骨盆的最大应力更高。两个重建骨盆中的应力分布相似。最大应力集中在重建胫骨杆上，该应力小于重建股骨，因为应力分布接近螺钉。结论：重建的骨盆的稳定性较完整的骨盆弱，但重建的骨盆是有效的并且可以在较早的时间承受人体的重量。重建的骨盆的最大应力高于完整的骨盆，并且股骨重建有利于预防骨折。

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