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首页> 外文会议>12th Symposium on Bioluminescence and Chemiluminescence, Apr 5-9, 2002, Robinson College, University of Cambridge, UK >FLUORESCENT PROTEINS: WHO'S GOT 'EM AND WHY?
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FLUORESCENT PROTEINS: WHO'S GOT 'EM AND WHY?

机译：荧光蛋白：谁的基因表达和为什么？

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摘要

Each of us enters science with pre-conceived notions about our particular science and each picks up other notions from our mentors and our teachers. While some ideas begin as interesting hypotheses, such ideas have a way of self-solidifying. Some, by mere repetition, wind up being widely accepted. As we develop our own scientific careers, we create hypotheses to guide our work -- ones that may unduly influence our students and the readers of our papers. Almost always, creators of hypotheses do so for the best of reasons. Almost always, those who repeat the hypotheses have equally noble intentions. All fields have to deal with inadvertent solidification of unproven hypotheses. For decades, DNA was thought to contain no information. Protein was the preferred storehouse of genetic information. It took substantial effort by many scientists to overcome this notion. A couple of them did so with paper models of nucleoside bases in a bicycle shop in Cambridge, England. Even when the central dogma was formulated, arrows all pointed from left to right. There was no reverse transcriptase to catalyze the synthesis of DNA from an RNA template.
机译：我们每个人都以对我们特定科学的先入为主的观念进入科学，并且每个人都从我们的导师和老师那里汲取其他观念。虽然某些想法开始时是有趣的假设，但这些想法有一种自我巩固的方式。有些仅仅是重复，最终被广泛接受。随着我们发展自己的科学事业，我们会提出假设来指导我们的工作-这些假设可能会对我们的学生和论文读者产生不适当的影响。假设的创造者几乎总是出于最好的原因而这样做。几乎总是重复那些假设的人有着同样崇高的意图。所有领域都必须处理未经证实的假设的疏忽巩固。几十年来，人们一直认为DNA不包含任何信息。蛋白质是遗传信息的首选仓库。为了克服这个想法，许多科学家付出了巨大的努力。他们中的一些人在英格兰剑桥的一家自行车店中使用核苷碱基的纸模型进行了建模。即使制定了中央教条，箭头也都从左到右指向。没有逆转录酶可催化从RNA模板合成DNA。

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