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首页> 外文会议>12th Symposium on Bioluminescence and Chemiluminescence, Apr 5-9, 2002, Robinson College, University of Cambridge, UK >CHEM1LUMINESCENT EXCITATION AND THE PHOTODYNAMIC EFFECT ON BACTERIAL STRAINS
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CHEM1LUMINESCENT EXCITATION AND THE PHOTODYNAMIC EFFECT ON BACTERIAL STRAINS

机译：化学发光激发及对细菌菌株的光动力效应

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摘要

It is possible to use the chemiexcited photodynamic effect for the killing of bacteria. The possibility depends on combination of the type of bacterial wall and photosensitizer. The photosensitizers do not affect gram-negative bacterial strains. The chemiexcitation generally depends on the phase of bacterial growth, but during the log phase and stationary phase it seams to be time independent. We also found that the chemiexcitation is independent on the energizers (PH or LU). In summary: the MIC for used photosensitizers on gram-positive bacterial strain Staphylococcus aureus is lower after chemiexcitation: for ClAlPcS_2 163 times, for ZnPcS_2 178 times, for methylene blue more than 10 times, for eosin B 16 times, for eosin Y only more than 3 times and for fluorescein only 2.5 times.
机译：可以利用化学激发的光动力作用来杀死细菌。可能性取决于细菌壁和光敏剂类型的组合。光敏剂不影响革兰氏阴性细菌菌株。化学激发通常取决于细菌生长的阶段，但是在对数阶段和固定阶段，化学接缝是与时间无关的。我们还发现，化学激发独立于激励器（PH或LU）。总结：化学激发后，革兰氏阳性金黄色葡萄球菌所用光敏剂的MIC较低：ClAlPcS_2 163倍，ZnPcS_2 178倍，亚甲基蓝10倍以上，曙红B 16倍，曙红Y仅更多超过3倍，而荧光素仅为2.5倍。

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