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Repeatability of Pressure Oscillation Amplitudes during the Interrupter Measurement of Respiratory Resistance

机译:中断测量呼吸阻力时压力波动幅度的可重复性

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Interrupter resistance (Rint) technique for as sessing respiratory mechanics requires minimal cooperation and can therefore be successfully performed in young children. Analysis of recorded oscillations of the mouth pressure (Pmo) has been suggested to provide additional indices of change in airway mechanics. The aim of this study was to establish the repeatability of pressure oscillation amplitudes. Children performed two sets of Rint measurements. Fur ther analysis of Pmo tracings was performed using MATLAB software. Pmo data were normalized to the last recorded pres sure and afterwards oscillation amplitudes (Amp) were found as the difference between the first Pmo maximum and mini mum. Intra-measurement repeatability was assessed by the coefficient of variation (CV) and between-test repeatability -by the coefficient of repeatability (CR). 92 young children (aged 3 to 7 years) were studied (49 of them healthy, 18 wheezers and 25 coughers). Median CV val ues for both measurements were 14% and 15% for Rint, and 14% and 13% for Amp. Our between-test Rint repeatability was similar to that of previous studies (CR was 0.23 kPa·L~(-1)·s or 33.3% of baseline value). CR for Amp was 0.24 or 27.6% of baseline value. There was no significant difference between groups of children. We measured short term repeatability for the most simple pressure oscillation amplitude and found that this is similar to Rint repeatability.
机译:用于评估呼吸力学的灭弧室电阻(Rint)技术需要最少的配合,因此可以在幼儿中成功实施。有人建议分析记录的口腔压力波动(Pmo),以提供气道力学变化的其他指标。这项研究的目的是建立压力振荡幅度的可重复性。孩子们进行了两组Rint测量。使用MATLAB软件对Pmo示踪进行了进一步分析。将Pmo数据归一化为最后记录的压力,然后将振荡幅度(Amp)作为第一个Pmo最大值与最小值之间的差值进行发现。通过变异系数(CV)和测试间重复性-通过重复性系数(CR)评估测量内重复性。研究了92名3至7岁的幼儿(其中49名健康,18名喘息者和25名咳嗽者)。两次测量的中值CV值对于Rint分别为14%和15%,对于Amp为14%和13%。我们的测试间Rint重复性与以前的研究相似(CR为0.23 kPa·L〜(-1)·s或基线值的33.3%)。 Amp的CR为基准值的0.24或27.6%。儿童组之间没有显着差异。我们测量了最简单的压力振荡幅度的短期可重复性,发现这与Rint可重复性相似。

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