Design consideration for descanned laminar optical tomography with EMCCD camera

机译：使用EMCCD相机进行反扫描层流光学层析成像的设计注意事项

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Current Laminar Optical Tomography (LOT) systems differ in their optical design, mainly in scanning mode strategies and detector selection. Herein, we investigate the design for an LOT system with an Electron Multiplying CCD camera in de-scanning mode. In de-scanning mode, the image of the detectors is scanned on the surface of the sample in conjunction with the raster scanned illumination spot. De-scanning 2D detector array yields high-density spatial sampling of the target with parallel data acquisition and high SNR. In this work, we investigate the effect of detector array configuration on the quality of reconstructions. Associated with l-norm, due its better performance over conventional methods such as conjugate gradient or least square, 2D detector arrays provides high fidelity reconstructions with high-resolution.

机译：当前的层流光学层析成像（LOT）系统的光学设计有所不同，主要在于扫描模式策略和检测器选择。在本文中，我们研究了采用电子倍增CCD相机在反扫描模式下的LOT系统的设计。在取消扫描模式下，将检测器的图像与光栅扫描的照明光斑一起扫描到样品的表面上。取消扫描2D检测器阵列可对目标进行高密度空间采样，并具有并行数据采集和高SNR。在这项工作中，我们调查了探测器阵列配置对重建质量的影响。与l范数相关联，由于其优于常规方法（例如共轭梯度或最小二乘）的2D检测器阵列的性能更好，因此可以提供高分辨率的高保真度重建。

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来源
《2014 40th Annual Northeast Bioengineering Conference》|2014年|1-2|共2页
会议地点 Boston MA(US)
作者
Ozturk M.S.; Intes X.; Fugang Yang;
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作者单位

Biomed. Eng. Dept., Rensselaer Polytech. Inst., Troy, NY, USA;

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会议组织
原文格式 PDF
正文语种 eng
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关键词
CCD image sensors; biomedical optical imaging; data acquisition; image reconstruction; lighting; medical image processing; noise; optical tomography; EMCCD camera; descanned LOT system design; electron multiplying CCD camera; high-density spatial sampling; illumination spot scanning; image reconstruction; laminar optical tomography; parallel data acquisition; signal-to-noise ratio; Arrays; Cameras; Detectors; Fluorescence; Image reconstruction; Optical imaging; Tomography; 2D array; LP norm; de-scanned; tomography;

机译：CCD图像传感器;生物医学光学成像;数据采集;图像重建;照明;医学图像处理;噪声;光学层析成像; EMCCD相机;反扫描LOT系统设计;电子倍增CCD相机;高密度空间采样;照明点扫描;图像重建层状光学层析成像;并行数据采集;信噪比;阵列;相机;检测器;荧光;图像重建;光学成像;层析成像;二维阵列; LP规范;反扫描;层析成像;;

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专利

1. OPTIMIZATION OF DESIGN PARAMETERS FOR FLUORESCENCE LAMINAR OPTICAL TOMOGRAPHY [J] . CHEN YU, CHEN CHAO-WEI Journal of innovative optical health sciences . 2011,第03期

机译：荧光层流光学X线摄影术设计参数的优化
2. Adaptive optics fundus camera/Optical coherence tomography system for high resolution retinal imaging using a compact design [J] . Matthias Salas, Xavier Levecq, Barbara Lamory, Investigative ophthalmology & visual science . 2016,第12期

机译：自适应光学眼底照相机/光学相干断层扫描系统，用于紧凑型设计的高分辨率视网膜成像
3. Adaptive optics fundus camera/Optical coherence tomography system for high resolution retinal imaging using a compact design [J] . Matthias Salas, Xavier Levecq, Barbara Lamory, Investigative ophthalmology & visual science . 2016,第12期

机译：自适应光学眼底照相机/光学相干断层扫描系统，用于紧凑型设计的高分辨率视网膜成像
4. SNR characterization of Mesoscopic Fluorescence Molecular Tomography with EMCCD camera [C] . Ji Robin, Ozturk Mehmet S., Intes Xavier 2015 41st Annual Northeast Biomedical Engineering Conference . 2015

机译：用EMCCD相机表征介观荧光分子层析成像的SNR表征
5. Design, Implementation, and Evaluation of a Fluorescence Laminar Optical Tomography Scanner for Brain Imaging. [D] . Sheikhzadeh, Mahya. 2016

机译：用于大脑成像的荧光层流光学层析成像扫描仪的设计，实现和评估。
6. Design considerations for polarization-sensitive optical coherence tomography with a single input polarization state [O] . Kristen L. Lurie, Tobias J. Moritz, Audrey K. Ellerbee 2012

机译：具有单输入偏振态的偏振敏感光学相干层析成像的设计注意事项
7. Calibration on the Spot of EMCCD Cameras for Super Resolution Microscopy [O] . Mortensen Kim I., Flyvbjerg Henrik 2013

机译：用于超分辨率显微镜的现场EMCCD相机校准

Design consideration for descanned laminar optical tomography with EMCCD camera

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