首页> 外文会议>2015 41st Annual Northeast Biomedical Engineering Conference >SNR characterization of Mesoscopic Fluorescence Molecular Tomography with EMCCD camera
【24h】

SNR characterization of Mesoscopic Fluorescence Molecular Tomography with EMCCD camera

机译:用EMCCD相机表征介观荧光分子层析成像的SNR表征

获取原文
获取原文并翻译 | 示例

摘要

Progress in bio-printing techniques has accentuated the need for non-invasive imaging modalities with high sensitivity, high resolution, and imaging depth of a few millimeters. Mesoscopic Fluorescence Molecular Tomography (MFMT) is a promising imaging modality for 3D localization and quantification of fluorescent labeled cells in thick scaffolds. Here we report on the characterization of our second generation MFMT system which uses an Electron-Multiplying charge coupled device (EMCCD). More precisely, we report on the effects of EM gain and deep cooling of the camera on signal-to-noise ratio (SNR) and hence the sensitivity. Experimental results showed that these parameters, when used in conjunction, increased SNR by at least 3 fold.
机译:生物打印技术的进步突显了对具有高灵敏度,高分辨率和几毫米成像深度的非侵入性成像方式的需求。介观荧光分子层析成像(MFMT)是用于厚支架中荧光标记细胞的3D定位和定量的一种有前途的成像方法。在这里,我们报告使用电子倍增电荷耦合器件(EMCCD)的第二代MFMT系统的特性。更准确地说,我们报告了EM增益和相机的深度冷却对信噪比(SNR)以及灵敏度的影响。实验结果表明,这些参数结合使用时,SNR至少提高3倍。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号