首页> 外文会议>26th European conference on biomaterials 2014 >Collagen(Ⅰ)-Poly(Glycerol Sebacate)/Poly(Butylene Succinate-Dilinoleate) Fibrous Scaffolds for Cardiac Tissue Engineering
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Collagen(Ⅰ)-Poly(Glycerol Sebacate)/Poly(Butylene Succinate-Dilinoleate) Fibrous Scaffolds for Cardiac Tissue Engineering

机译:用于心脏组织工程的胶原蛋白(Ⅰ)-聚癸二酸甘油酯/丁二酸丁二酯-聚己二酸纤维支架

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摘要

Newly developed collagen(Ⅰ)-PGS/PBS-DLA hybrid fibres were successfully fabricated by electrospinning. Immunostaining analyses showed that the hybrid fibres promoted CM adhesion, where CMs exhibited well developed sarcomeric structures comparable to those when grown on fibronectin, the natural matrix protein of CMs. Collagen(Ⅰ)-PGS/PBS-DLA concludes to be a promising novel functional biomimetic nanofiber for cardiac tissue engineering.
机译:通过电纺成功制备了新开发的胶原蛋白(Ⅰ)-PGS / PBS-DLA杂化纤维。免疫染色分析表明,杂化纤维促进了CM的粘附,其中CM表现出与在CM的天然基质蛋白纤连蛋白上生长时相当的发达的肌节结构。结论:胶原蛋白(Ⅰ)-PGS / PBS-DLA是一种有前途的新型功能仿生纳米纤维,可用于心脏组织工程。

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  • 会议地点 Liverpool(GB)
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    Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, 91058 Erlangen, Germany;

    Experimental Renal and Cardiovascular Research, Department of Nephropathology, Institute of Pathology, University of Erlangen-Nuernberg, 91054 Erlangen, Germany;

    Polymer Institute, Division of Biomaterials and Microbiological Technologies, West Pomeranian University of Technology, Szczecin, Al. Piastow 45, Poland;

    Polymer Institute, Division of Biomaterials and Microbiological Technologies, West Pomeranian University of Technology, Szczecin, Al. Piastow 45, Poland;

    Experimental Renal and Cardiovascular Research, Department of Nephropathology, Institute of Pathology, University of Erlangen-Nuernberg, 91054 Erlangen, Germany;

    Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, 91058 Erlangen, Germany;

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