首页> 外文会议>The 2nd International Conference on Risk Analysis and Crisis Response(第二届风险分析与危机反应国际学术研讨会) >Comparative in Vitro Cytotoxicity Assessment of Some Manufactured Nano-particulate Materials
【24h】

Comparative in Vitro Cytotoxicity Assessment of Some Manufactured Nano-particulate Materials

机译:某些人造纳米颗粒材料的体外细胞毒性比较评估

获取原文
获取原文并翻译 | 示例

摘要

The aim of this study was to investigate the in vitro cytotoxicity and inflammation of human bronchial epithelial cells (BEAS-2B) after exposure to various type and size of nanoparticles such as Ag, Au, Fe203, TiO2, and CNT. The cell viability was dose-dependently reduced for all materials except Au. The cytotoxicity of Ag and MWCNT was increased due to their smaller size. We have found that the Ag, CNT and small size Fe203 lead to cellular toxicity but Au and TiO2 were not toxic compared to other nano-materials. Depending on the size, though cytotoxicity was not observed in >100nm size, but medium toxicity observed in 50-100nm and we confirm that the <50nm NPs be significant toxicity.
机译:这项研究的目的是研究人类支气管上皮细胞(BEAS-2B)在暴露于各种类型和大小的纳米粒子(例如Ag,Au,Fe2O3,TiO2和CNT)后的体外细胞毒性和炎症。除Au外,所有材料的细胞活力均呈剂量依赖性降低。 Ag和MWCNT由于其较小的尺寸而增加了细胞毒性。我们已经发现,Ag,CNT和小尺寸的Fe2O3会导致细胞毒性,但与其他纳米材料相比,Au和TiO2无毒。取决于大小,尽管在> 100nm大小时未观察到细胞毒性,但在50-100nm中观察到了中等毒性,我们证实<50nm NPs具有明显的毒性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号