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首页> 外文会议>3rd frontiers in biomedical devices conference 2008 : Imaging and anatomic interaction ; Simulation and testing ; Device testing ... >MICROPALLET TECHNOLOGY FOR INVESTIGATING TUMOR CELLULAR PROFILES AND ANALYSIS OF RARE CELL SUBSETS
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MICROPALLET TECHNOLOGY FOR INVESTIGATING TUMOR CELLULAR PROFILES AND ANALYSIS OF RARE CELL SUBSETS

机译：研究肿瘤细胞特征的微球技术和稀有细胞亚群的分析

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Rationally designed, individualized therapeutic strategies have long been a desired objective for breast cancer patients and clinicians as an estimated 178,480 new cases of invasive breast cancer will be diagnosed among women in the United States this year and over 40,000 women are expected to die from the disease. [1] The increasing appreciation of breast tumor cellular heterogeneity raises fundamental questions as to the relative contributions of cellular subsets to the biologic behavior of an individual patient's tumor. [2] As such, it has become increasingly clear that in many cases, an individualized strategy for the treatment of breast cancer would be of great benefit, and that the ability to isolate relevant cellular subsets from the main tumor population is one of the critical limits to accomplishing this goal.
机译：长期以来，合理设计，个性化的治疗策略一直是乳腺癌患者和临床医生的理想目标，因为据估计，今年美国女性中将诊断出178,480例新的浸润性乳腺癌病例，预计将有40,000多例女性死于该疾病。 [1]对乳腺肿瘤细胞异质性的日益重视提出了一些基本问题，即细胞亚群对单个患者肿瘤生物学行为的相对贡献。 [2]因此，越来越清楚的是，在许多情况下，个体化治疗乳腺癌的策略将大有裨益，而从主要肿瘤人群中分离相关细胞亚群的能力是关键之一。实现这个目标的局限性。

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