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Usage of change-related non-invasive imaging paradigms to investigate the representation of sound in the human brain

机译:使用与变化有关的非侵入性成像范例来研究人脑中声音的表示

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To efficiently recognize and localize sounds is of paramount importance for our everyday life. However, the computational processes that underlie these capabilities in the human brain are still not fully understood. A powerful tool to study the representation and transformation of sensory information in the human brain are change-related paradigms. This text reviews three recent examples from our lab that employed change-related paradigms with different brain imaging modalities to characterize the representation of sounds in the human brain. Specifically, a first experiment used functional magnetic resonance imaging and signal response suppression after stimulus repetition to characterize the representation of natural sounds. A second magnetoencephalo-graphic experiment, used a two-tone paradigm to describe the time-course of adaptation to natural sounds. In a third experiment, we employed a spatial mismatch negativity oddball paradigm during electroencephalography to test for head-related versus allocentric representation of sound sources in the human brain.
机译:有效识别和定位声音对于我们的日常生活至关重要。但是,仍无法完全理解人脑中这些功能的基础计算过程。研究人脑中感官信息的表示和转换的强大工具是与变化有关的范例。本文回顾了我们实验室的三个最近的例子,这些例子采用了与变化有关的范例,它们具有不同的大脑成像方式来表征人脑中声音的表示。具体而言,第一个实验在重复刺激后使用功能性磁共振成像和信号响应抑制来表征自然声音的表现。第二个脑磁图实验,使用了两个音调范例来描述适应自然声音的时间过程。在第三个实验中,我们在脑电图检查中采用了空间失配负性奇异球范式,以测试人脑中声源的头部相关与异源表示。

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