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Computing Radial Basis Function Support Vector Machine using DNA via Fractional Coding

机译:通过分数编码使用DNA计算径向基函数支持向量机

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This paper describes a novel approach to synthesize molecular reactions to compute a radial basis function (RBF) support vector machine (SVM) kernel. The approach is based on fractional coding where a variable is represented by two molecules. The synergy between fractional coding in molecular computing and stochastic logic implementations in electronic computing is key to translating known stochastic logic circuits to molecular computing. Although inspired by prior stochastic logic implementation of the RBF-SVM kernel, the proposed molecular reactions require non-obvious modifications. This paper introduces a new explicit bipolar-to-unipolar molecular converter for intermediate format conversion. Two designs are presented; one is based on the explicit and the other is based on implicit conversion from prior stochastic logic. When 5 support vectors are used, it is shown that the DNA RBF-SVM realized using the explicit format conversion has orders of magnitude less regression error than that based on implicit conversion. CCS CONCEPTS • Applied computing → Molecular structural biology; •Hardware → Biology-related information processing;
机译:本文介绍了一种合成分子反应以计算径向基函数(RBF)支持向量机(SVM)内核的新颖方法。该方法基于分数编码,其中变量由两个分子表示。分子计算中的分数编码与电子计算中的随机逻辑实现之间的协同作用是将已知的随机逻辑电路转换为分子计算的关键。尽管受RBF-SVM内核的先前随机逻辑实现的启发,但提出的分子反应需要非显而易见的修改。本文介绍了一种用于中间格式转换的新型显式双极至单极分子转换器。提出了两种设计;一个是基于显式的,另一个是基于先前随机逻辑的隐式转换。当使用5个支持向量时,表明使用显式格式转换实现的DNA RBF-SVM比基于隐式转换的回归误差小几个数量级。 CCS概念•应用计算→分子结构生物学; •硬件→生物相关信息处理;

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