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Bt brassicas for DBM control:The CIMBAA public/private partnership

机译:用于DBM控制的Bt芸苔:CIMBAA公共/私人伙伴关系

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Cabbage and cauliflower are major dietary items in Asia and much of Africa but diamondback moth (DBM),Plutella xlosteUa(L.),and other lepidopterous pests routinely reduce yields by>30%even in insecticide protected crops.Most are sprayed at least weekly with insecticides,adding significantly to production costs and creating producer and consumer health hazards.A public/private partnership,The Collaboration on Insect Managementfor Brassicas in Asia and africa(www.CIMBAA.org)has been formed between universities in UK,USA and Australia,AVRDC-The World Vegetable Center,and Nunhems Seed Company,to develop,test and,if appropriate,register pyramided Bt gene transgenie cabbage and cauliflower as a major contribution to brassica IPM. Tightly linking the two genes(for Cry1 B and Cry1 C)in one cartridge is intended to virtually eliminate the risk of accidental separation during breeding. Phase Ⅰ of the programme-country needs and technical feasibility assessment and demonstration of stakeholder support. Is complete.Phase Ⅱ-development of the germplasm and laboratory and field tests of emcacv.biosafety and sustainability. Is well advanced.Risk assessments are being undertaken,and IPM/resistance management strategies worked out.Laboratory assessment has shown the two proteins to have low LD50s against diamondback moth,Crodicolomis pavonana,HeUula undalis and Pieris spp.CIMBAA is completing initial greenhouse trials with the material in India and is now selecting the elite events for eventual registration in India. If biological performance and environmental assessments are positive,the chosen material should enter PhaseⅢ-registration trials. In India in 2008.Phase Ⅳ-registration and commercialisation in the first of a cascade of identified countries in need of the material could come as early as 2012.An unfolding communications strategy is commencing with meetings on technical and public interest issues being held in India.CIMBAA's intention is to have the ownership of the developed plant material and the necessary IP in the hands of a public partner,for dissemination for further breeding and commercialisation under strict stewardship guidelines,to interested seed producers in countries in which the material is registered,without restrictive licenee or other fees.
机译:卷心菜和花椰菜是亚洲和非洲大部分地区的主要饮食,但小菜蛾,小菜蛾和其他鳞翅目害虫即使在使用杀虫剂的农作物中也通常使单产降低> 30%。大多数至少每周喷洒一次在英国,美国和澳大利亚的大学之间已经建立了公共/私人合作伙伴关系,即亚洲和非洲的芸苔属昆虫管理合作组织(www.CIMBAA.org)。 ,世界蔬菜中心AVRDC和Nunhems种子公司开发,测试并酌情注册金字塔状的Bt基因转基因甘蓝和花椰菜,这是对芸苔IPM的主要贡献。将两个基因(对于Cry1 B和Cry1 C)紧密连接在一起,实际上可以消除育种过程中意外分离的风险。方案国家的第一阶段需求和技术可行性评估以及利益相关者支持的证明。第二阶段:种质的开发以及生物安全性和可持续性的实验室和田间试验。目前已经进行了风险评估,并制定了IPM /抗性管理策略。实验室评估表明,这两种蛋白质对小菜蛾的LD50较低,Crodicolomis pavonana,HeUula undalis和Pieris spp。印度的资料,现在正在选择精英赛事,以便最终在印度注册。如果生物学性能和环境评估为阳性,则所选材料应进入Ⅲ期注册试验。在2008年的印度,最早需要该材料的已查明国家级的第Ⅳ期注册和商业化最早可能会在2012年开始。一种正在开展的传播战略正在印度举行有关技术和公共利益问题的会议开始。 .CIMBAA的目的是将已开发的植物材料的所有权和必要的IP所有权掌握在公共合作伙伴的手中,以便在严格的管理指导下,将这些植物材料传播给在其注册国的感兴趣的种子生产商,没有限制性licenee或其他费用。

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