Dna vaccination of rhesus monkeys against hepatitis B virus: effects of routes and formulations

机译：恒河猴对乙型肝炎病毒的DNA疫苗接种：途径和配方的影响

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In our previous work, we found that direct intramuscular injection (IM) of DNA vaccine encoding HBsAg could stimulate higher levels of specific antibody than intradermal administration (ID) in mice. To obtain more relevant data on efficacy of DNA vaccine for human use, we carried out such studies in primate-Rhesus Monkeys.

机译：在我们以前的工作中，我们发现，与在小鼠体内进行皮内给药（ID）相比，直接肌内注射编码HBsAg的DNA疫苗可刺激更高水平的特异性抗体。为了获得有关人类使用的DNA疫苗功效的更多相关数据，我们在灵长类动物-猕猴中进行了此类研究。

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《7th China-Japan International Congress of Microbiology Shanghai Symposium-2000 4-6 August 2000 Shanghai》|2000年|p.124|共1页
会议地点 Shanghai(CN);Shanghai(CN)
作者
Yuan Zheng-hong; Zheng Ling-jie; qiu Hai-jun; He Lifang; Wen Yumei;
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正文语种 eng
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专利

1. Robust vaccine-elicited cellular immune responses in breast milk following systemic Simian Immunodeficiency Virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys. [J] . Wilks AB, Christian EC, Seaman MS, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2010,第11期

机译：系统性猿猴免疫缺陷病毒DNA初免和活病毒载体对母乳喂养的恒河猴进行了强有力的疫苗诱导的细胞免疫反应。
2. Robust vaccine-elicited cellular immune responses in breast milk following systemic Simian Immunodeficiency Virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys. [J] . Wilks AB, Christian EC, Seaman MS, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2010,第11期

机译：系统性猿猴免疫缺陷病毒DNA初免和活病毒载体对母乳喂养的恒河猴进行了强有力的疫苗诱导的细胞免疫反应。
3. Robust vaccine-elicited cellular immune responses in breast milk following systemic Simian Immunodeficiency Virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys. [J] . Wilks AB, Christian EC, Seaman MS, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2010,第11期

机译：系统性猿猴免疫缺陷病毒DNA初免和活病毒载体对母乳喂养的恒河猴进行了强有力的疫苗诱导的细胞免疫反应。
4. Dna vaccination of rhesus monkeys against hepatitis B virus: effects of routes and formulations [C] . Yuan Zheng-hong, Zheng Ling-jie, qiu Hai-jun, China-Japan international congress of microbiology . 2000

机译：DNA接种恒河猴对乙型肝炎病毒的疫苗：途径和制剂的影响
5. A rhesus monkey model of respiratory syncytial virus (RSV) to evaluate the immunogenicity and protective efficacy of a DNA vaccine. [D] . Vaughan, Kerrie Colleen McArthur. 2002

机译：呼吸道合胞病毒（RSV）的恒河猴模型，用于评估DNA疫苗的免疫原性和保护功效。
6. Immune response to a hepatitis B DNA vaccine in Aotus monkeys: a comparison of vaccine formulation route and method of administration. [O] . R. A. Gramzinski, C. L. Millan, N. Obaldia, 1998

机译：Aotus猴对乙型肝炎DNA疫苗的免疫反应：疫苗配方途径和给药方法的比较。
7. DNA Vaccination with the Hantaan Virus M Gene Protects Hamsters against Three of Four HFRS Hantaviruses and Elicits a High-Titer Neutralizing Antibody Response in Rhesus Monkeys [O] . Hooper, J. W., Custer, D. M., Thompson, E., 2001

机译：用汉坦病毒M基因进行DNA疫苗接种可保护仓鼠免受四种HFRS汉坦病毒的侵害，并在恒河猴中引发高滴度中和抗体反应

Dna vaccination of rhesus monkeys against hepatitis B virus: effects of routes and formulations

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