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首页> 外文会议>Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIII >Optical characteristics of prostate tissues and the key chromophores and fluorophores within tissues related to carcinogenesis
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Optical characteristics of prostate tissues and the key chromophores and fluorophores within tissues related to carcinogenesis

机译：前列腺组织的光学特性以及与癌变相关的组织中的主要发色团和荧光团

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摘要

Tissues are an impressive complex creation comprised of a vast of assortment of molecules, structures and functional units. Despite this overwhelming complexity, we may still discuss average optical properties as long as we realize the limitations involved. There are five independent macroscopic parameters that are believed to characterize light propagation in tissue: the index of refraction (n), the absorption coefficient (μ_a), the scattering coefficient (μ_s), the reduced scattering coefficient (μ'_s), and the scattering anisotropy (g). This paper summarizes the Optical characteristics of tissue of prostate tissues ex vivo and the key fluorophores related to carcinogenesis. The absorption coefficient (μ_a) describes the effectiveness of light absorbed by certain chromophore. The key spectra fingerprints of water were introduced to distinguish different water contents in normal and cancerous prostate tissues. Fluorescence occurs when a molecule, atom or nanostructure relaxes to its ground state after being electrically excited. There are three fluorescence parameters of interest we may concern in tissue optics: the fluorescence lifetime (τ_f), the fluorescence quantum yield (Φ) and the fluorescence emission peak (λ_(max)). The key wavelengths which can be used for cancer detection were reviewed. Scattering of light occurs in media which contains fluctuations in the refractive index n. Tissue ultrastructure extends from membranes to membrane aggregates to collagen fibers to nuclei to cells, which may be an alternative way to detect cancer in tissues.
机译：组织是令人印象深刻的复杂创造，由各种各样的分子，结构和功能单元组成。尽管存在如此巨大的复杂性，但只要我们意识到所涉及的限制，我们仍然可以讨论平均光学性能。据信有五个独立的宏观参数可以表征光在组织中的传播：折射率（n），吸收系数（μ_a），散射系数（μ_s），降低的散射系数（μ'_s）和散射各向异性（克）。本文总结了离体前列腺组织的光学特性以及与癌变有关的关键荧光团。吸收系数（μ_a）描述了某些生色团吸收的光的有效性。引入水的关键光谱指纹以区分正常和癌性前列腺组织中的不同水分含量。当分子，原子或纳米结构在被电激发后松弛到其基态时发生荧光。我们在组织光学中可能需要关注三个荧光参数：荧光寿命（τ_f），荧光量子产率（Φ）和荧光发射峰（λ_（max））。审查了可用于癌症检测的关键波长。光的散射发生在包含折射率n波动的介质中。组织超微结构从膜延伸到膜聚集体，再到胶原纤维再到细胞核，再到细胞，这可能是检测组织中癌症的另一种方法。

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