• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Advanced Biomedical and Clinical Diagnostic Systems III; Progress in Biomedical Optics and Imaging; vol.6 no.7 >Ultrasound-tagged light assessment of osteoporosis
【24h】

Ultrasound-tagged light assessment of osteoporosis

机译：超声标记骨质疏松症的光评估

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

There have been several attempts to detect bone structural changes using optical techniques. H.G. Eberle et al. have used ultrafast optical techniques on the finger in trans-illumination and have shown an excellent correlation between their measurements of the scattering coefficient and bone mineral density obtained using dual X-ray absorption (DXA) imaging. Encouraged by these results, we have developed a system based on the combination of cw laser light and low-frequency ultrasound to probe the bone structure. The physical principle of this system is the detection of laser light diffusing in the bone tissue modulated ("tagged") by a low-frequency ultrasound pulse, which allows a local measurement of the attenuation coefficient. The basic assumption of the technique is that the main factor of attenuation changes in the bone of elderly patients is a scattering change due to osteoporosis, and therefore attenuation measurements directly reflect the scattering properties of the bone. We present a preliminary series of clinical experiments showing that this technique allows determining the bone scattering modification inside the trabecular bone. In this series of clinical experiments, the scattering coefficient determined using the optical technique is compared with the bone mineral density obtained using dual X-ray absorption in a group of 9 patients. A correlation of 0.84 (p=0.05) was found, showing the potential of this technique for the assessment of osteoporosis.
机译：已经进行了使用光学技术检测骨骼结构变化的多种尝试。 H.G. Eberle等。已在透射照明中在手指上使用了超快光学技术，并且显示了使用双X射线吸收（DXA）成像获得的散射系数测量值与骨矿物质密度之间的极好的相关性。受这些结果的鼓舞，我们开发了一种基于连续波激光和低频超声相结合的系统来探测骨骼结构。该系统的物理原理是检测在低频超声脉冲调制（“标记”）的骨组织中扩散的激光，这允许对衰减系数进行局部测量。该技术的基本假设是，老年患者的骨骼衰减变化的主要因素是由于骨质疏松引起的散射变化，因此衰减测量结果直接反映了骨骼的散射特性。我们提供了一系列初步的临床实验，表明该技术可以确定小梁骨内部的骨散射变化。在这一系列的临床实验中，将使用光学技术确定的散射系数与使用双X射线吸收获得的9位患者的骨矿物质密度进行比较。发现相关系数为0.84（p = 0.05），表明该技术可用于评估骨质疏松症。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号