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首页> 美国政府科技报告 >Risk of Early Onset Osteoporosis Due to Spaceflight: Record 10 (MRL No. 01, Osteoporosis)-BASELINE
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Risk of Early Onset Osteoporosis Due to Spaceflight: Record 10 (MRL No. 01, Osteoporosis)-BASELINE

机译：太空飞行造成早期骨质疏松症的风险：记录10（mRL No. 01，骨质疏松症）-BasELINE

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Osteoporosis is a skeletal syndrome that is characterized by low bone mass and severe structural deterioration. This condition can be due to aging or an extrinsic factor(s). Spaceflight-induced bone loss is classified as the latter (Secondary Osteoporosis) and is not contingent upon age. Bone mineral loss occurs in microgravity due to unloading of the skeletal system, with average loss rates of approximately 1% per month. It is unclear whether this bone mineral density will stabilize at a lower level, or continue to diminish. It is unknown if fractional gravity, present on the moon and Mars would mitigate the loss. Likewise, the impact of multiple long -duration missions or of cumulative time in space is not yet established. Space exposure could be a risk factor for Secondary Osteoporosis after return to earth and could put crewmembers at greater risk of osteoporosis-related fractures at an earlier age than expected for a terrestrial peer group. Greater understanding of the mechanisms for bone atrophy in microgravity, and for recovery after return, is necessary to frame this risk, as well as to understand how current and future osteoporosis treatments may be employed.

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