首页> 外文会议>Computational Neuroscience Meeting (CNS'01) Jul, 2001 Monterey, California >Topographic restoration of visual spatial attention in the cortically blind cat
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Topographic restoration of visual spatial attention in the cortically blind cat

机译:皮质盲猫视觉空间注意力的地形恢复

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We explored the mechanisms of spatial attention in the cat with a combination of permanent and reversible lesion techniques. Animals with large unilateral visual cortical lesions displayed profound blindness of contralesional visual space. However, cooling deactivation of either posterior parietal cortex or the superior colliculus (SC) in the contralesional half of the brain restored visual orienting responses in the blind hemifield. Interestingly, gradual SC deactivation by decreasing cooling loop temperatures produced a topographic restoration of orienting responses, starting at the midline and progressing towards more peripheral eccentricities in the previously blind field. These effects can be explained within a computational model for spatial orienting, which represents the interhemispheric competition of bilateral brain structures that possess a topographic, center-magnified representation of the external visual space.
机译:我们结合了永久性和可逆性病变技术,探索了猫的空间注意力机制。单侧视觉皮层病变较大的动物表现出对侧视觉空间的严重失明。然而,大脑对侧一半的后顶叶皮质或上丘(SC)的冷却失活恢复了盲半场的视觉定向反应。有趣的是,通过降低冷却回路温度使SC逐渐失活,从而使定向响应在地形上得以恢复,从中线开始,在先前的盲区中逐渐向外围偏心方向发展。这些影响可以在用于空间定向的计算模型中解释,该模型表示具有外部视觉空间的地形,中心放大表示的双侧大脑结构的半球竞争。

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