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Superelastic NiTi Thin Film Small Vessel Graft For Vascular Repair

机译:NiTi超弹性薄膜小血管移植物修复

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摘要

Thin film NiTi produced by sputter deposition was used in the design of small vessel grafts intended to treat small vessel aneurysms. Thin film small vessel grafts were fabricated by "hot-target" DC sputter deposition. Both stress-strain curves and DSC curves were generated for the film used to fabricate small vessel grafts. The films used for small vessel grafts had an A_f temperatures of approximately 36 degrees allowing for body activated response from a micro-catheter. Thin film small vessel grafts were tested in a pulsatile flow loop in vitro. Small vessel grafts could be compressed into and easily delivery in < 3 Fr catheters. Theoretical frictional and wall drag forces on a thin film NiTi small vessel vascular graft were calculated and the radial force exerted by thin film small vessel grafts was evaluated theoretically and experimentally. In-vivo studies in swine confirmed that thin film NiTi small vessel grafts could be deployed accurately and consistently in the swine vascular system.
机译:通过溅射沉积产生的薄膜NiTi被用于设计用于治疗小血管瘤的小血管移植物。薄膜小血管移植物是通过“热靶”直流溅射沉积制成的。对于用于制造小血管移植物的膜,产生了应力-应变曲线和DSC曲线。用于小血管移植物的薄膜的A_f温度约为36度,允许微导管对人体进行激活。体外在脉动流回路中测试了薄膜小血管移植物。小血管移植物可被压缩并轻松放入<3 Fr导管中。计算了薄膜TiTi小血管移植物的理论摩擦力和壁阻力,并从理论和实验上评估了薄膜小血管移植物施加的径向力。猪的体内研究证实,NiTi薄膜小血管移植物可以在猪血管系统中准确,一致地部署。

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