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首页> 外文会议>Conference on Biomedical Applications of Micro-and Nanoengineering, Dec 16-18, 2002, Melbourne, Australia >DNA-BASED HIGH-DENSITY MEMORY DEVICES AND BIOMOLECULAR ELECTRONICS AT CSIO
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DNA-BASED HIGH-DENSITY MEMORY DEVICES AND BIOMOLECULAR ELECTRONICS AT CSIO

机译：CSIO的基于DNA的高密度存储设备和生物分子电子

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During the last half century the electronic components and computers have grown more and more powerful with the shrinking dimensions of transistors which is approaching 100nm with about a billion tiny devices working together on a single processor. The laws of quantum mechanics and limitations of materials and fabrication techniques restrict further reduction below 100nm. The most promising area is Biomolecular Electronics concerning design and fabrication of basic electronic components using biomolecules. Various organic polymers are being studied for visualization of individual molecular electronic wires and diode switches but we see enormous potential in use of DNA for such devices due to its inherent characteristics. This is because DNA can act as insulator semiconductor, conductor or superconductor depending upon the base sequence, length and orientation. The DNA can be coated selectively with metals with molecular level precision giving us capability to design molecular electronic components, such as, diode, triode, transistor, etc. This paper discusses the DNA based language developed by our group for coding and decoding any digital information in terms of DNA sequence. Basic arithmetical operations, such as, addition subtraction, multiplication, division and exponential have been defined in terms of DNA sequence and their validity has been demonstrated. Paper will also discuss our programme on study of DNA electrical behaviour in terms of sequence; length and orientation for development of biomolecular electronic components and for understanding DNA damaged chemistry.
机译：在过去的半个世纪中，随着晶体管尺寸的不断缩小，电子组件和计算机的功能越来越强大，晶体管的尺寸已逼近100nm，约有十亿个微型设备在单个处理器上协同工作。量子力学定律以及材料和制造技术的局限性限制了进一步减小到100nm以下。最有前途的领域是生物分子电子，涉及使用生物分子设计和制造基本电子组件。正在研究各种有机聚合物以可视化单个分子电子线和二极管开关，但是由于其固有的特性，我们看到将DNA用于此类设备的巨大潜力。这是因为取决于碱基序列，长度和方向，DNA可以充当绝缘体半导体，导体或超导体。 DNA可以选择性地被具有分子水平精度的金属包覆，从而使我们能够设计分子电子组件，例如二极管，三极管，晶体管等。本文讨论了我们小组开发的基于DNA的语言，用于编码和解码任何数字信息在DNA序列方面。基本的算术运算，如加减法，乘法，除法和指数法已根据DNA序列进行了定义，并证明了其有效性。本文还将就序列研究DNA电学行为的程序进行讨论。长度和方向，以开发生物分子电子元件并了解DNA损伤的化学反应。

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