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首页> 外文会议>Conference on Biomedical Optoacoustics Ⅲ Jan 20-21, 2002 San Jose, USA >Photo-induced acoustic spectra of biological tissues and photoacoustic tomography by phase-controlled focus algorithm
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Photo-induced acoustic spectra of biological tissues and photoacoustic tomography by phase-controlled focus algorithm

机译：相控聚焦算法对生物组织的光致声谱和光声层析成像

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摘要

Photoacoustic tomography has attracted high attention in recent years, because this imaging technique can combine the advantages of ultrasound and light to improve the image resolution and diagnostic depth of tissues. In this paper, spectrospopic feature of photo-induced acoustic signal generated in biological tissues are investigated, and its characteristics are analyzed in time domain and in frequency domain. The results show that spectrum of photoacoustic signal changes with the property of tissue sensitively. A spectrum-selective photoacoustic imaging might be a potential approach to diagnose special disease at the early stage. According to the spectral characteristics of photoacoustic signal, here, we present a photoacoustic tomography of real tissue to depth of ～12mm by selecting a wide-band high-sensitive detector. The time-resolved technique and a phase-controlled focus algorithm was used for image reconstruction, and a depth resolution up to ～10 μm and a lateral resolution about 300 μm were obtained.
机译：近年来，光声层析成像技术引起了人们的高度关注，因为这种成像技术可以结合超声和光的优势来提高图像分辨率和组织的诊断深度。本文研究了在生物组织中产生的光诱导声信号的频谱特征，并在时域和频域分析了其特征。结果表明，光声信号的频谱随组织特性的变化而变化。光谱选择性光声成像可能是早期诊断特殊疾病的潜在方法。根据光声信号的频谱特征，在这里，我们通过选择一个宽带高灵敏度检测器，对〜12mm深度的真实组织进行光声层析成像。利用时间分辨技术和相位控制的聚焦算法进行图像重建，获得了约〜10μm的深度分辨率和约300μm的横向分辨率。

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