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首页> 外文会议>Conference on Lasers in Dentistry IX Jan 26-27, 2003 San Jose, California, USA >Laser Biomodulation in bone implants: A Raman spectral study
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Laser Biomodulation in bone implants: A Raman spectral study

机译：骨植入物中的激光生物调制：拉曼光谱研究

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摘要

Healing is important for the success of the insertion of implants and for treating traumatic or pathologic injuries of the bone. Lasertherapy has been suggested as a mean of improving bone healing. Near infrared Raman spectroscopy was used to assess the amount of both inorganic and organic components of irradiated and control bone around dental implants inserted in to the tibia. Fourteen rabbits received a titanium implant on the tibia; eight of them were irradiated with λ830nm laser (Thera Lase, DMC, Sao Carlos, SP, Brazil, 21.5 J/cm~2, 10mW, spot size 0.60mm) and six acted as controls. The animals were sacrificed 15, 30 and 45 days after the surgery, and specimens were prepared for Raman spectroscopy, which was collected at every four points from each three thirds of the bone around the implants. The results showed significant differences in the concentration of inorganic components in irradiated specimens between 15 and 30days (p<0.05), 15 and 45 (p< 0.01); between irradiated and cortrols 30 and 45 days after surgery (p<0.01). Concentration of organic components was also significantly different between irradiated and controls in periods of 30 to 45 days after surgery. It is concluded that LLLT does improve bone healing and Raman Spectroscopy can safely assess this.
机译：愈合对于成功植入植入物以及治疗骨骼的外伤或病理损伤很重要。激光疗法被认为是改善骨愈合的一种手段。使用近红外拉曼光谱法评估插入到胫骨中的牙科植入物周围的辐照骨和对照骨的无机和有机成分的量。 14只兔子在胫骨上植入了钛金属植入物。其中八个用λ830nm激光（Thera Lase，DMC，Sao Carlos，SP，巴西，21.5 J / cm〜2、10mW，光斑尺寸0.60mm）照射，六个作为对照。手术后第15、30和45天将动物处死，并准备用于拉曼光谱的标本，该标本是从植入物周围每三分之三的骨头的每四个点收集的。结果表明，在15天和30天之间（p <0.05），15天和45天（p <0.01），辐照样品中无机成分的浓度存在显着差异。术后30至45天的辐照和皮质激素之间的差异（p <0.01）。手术后30到45天，受辐照和对照之间的有机成分浓度也存在显着差异。结论是LLLT确实改善了骨愈合，拉曼光谱法可以安全地对此进行评估。

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