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首页> 外文会议>Conference on Optical Diagnostics of Living Cells Ⅴ, Jan 23-25, 2002, San Jose, USA >Theoretical investigation of the signal-to-noise ratio for different fluorescence lifetime imaging techniques
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Theoretical investigation of the signal-to-noise ratio for different fluorescence lifetime imaging techniques

机译：不同荧光寿命成像技术信噪比的理论研究

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摘要

Using Monte-Carlo methods, we have investigated the signal-to-noise ratio obtainable for different fluorescence lifetime imaging methods. Quantum noise limited performance and mono-exponential decays were assumed. We have also investigated the importance of parameter choice and implementation for the different methods. In addition, our simulations were in many cases compared with analytical theoretical investigations. The results from the simulations proved to be in good agreement with the theoretical results. It was found that all the investigated lifetime imaging methods have the potential to produce a high signal-to-noise ratio, but careful attention must be paid to implementation method and parameter choice in order to get optimal results.
机译：使用蒙特卡洛方法，我们研究了不同荧光寿命成像方法可获得的信噪比。量子噪声限制了性能，并假设了单指数衰减。我们还研究了参数选择和实现对于不同方法的重要性。另外，我们的模拟在很多情况下都与分析理论研究进行了比较。仿真结果与理论结果吻合良好。已经发现，所有研究的寿命成像方法都有可能产生高信噪比，但是必须注意实现方法和参数选择，以获得最佳结果。

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