Measurement of Refractive Index Variation of Physiological Analytes using Differential Phase OCT

机译：使用微分相OCT测量生理分析物的折射率变化

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We report results of a study using differential phase optical coherence tomography (DP-OCT) for measurement of variation of refractive index (n) vs. analyte concentration (C) in translucent solutions and turbid tissue phantoms. Variation of refractive index with analyte concentration (dn/dC) in aqueous solutions of glucose, calcium chloride, magnesium chloride, sodium chloride, potassium chloride, potassium bicarbonate, urea, bovine serum albumin, and bovine globulin was measured. Obtained results demonstrated: (1) dn/dC for glucose is significantly greater than that of other analytes in the physiological range; and (2) high sensitivity of DP-OCT method for measurement of analyte concentration.

机译：我们报告了使用微分相光学相干断层扫描（DP-OCT）来测量半透明溶液和混浊组织体模中折射率（n）与分析物浓度（C）的变化的研究结果。测量了葡萄糖，氯化钙，氯化镁，氯化钠，氯化钾，碳酸氢钾，尿素，牛血清白蛋白和牛球蛋白水溶液中折射率随分析物浓度（dn / dC）的变化。获得的结果表明：（1）在生理范围内，葡萄糖的dn / dC显着高于其他分析物；（2）DP-OCT方法对分析物浓度的测量具有很高的灵敏度。

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来源
《Conference on Optical Diagnostics and Sensing IV; 20040127; San Jose,CA; US》|2004年|P.31-34|共4页
会议地点 San Jose CA(US)
作者
Kirill V. Larin; Taner Akkin; Thomas E. Milner; D. P. Dave; Massoud Motamedi; Rinat O. Esenaliev;
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Center for Biomedical Engineering The University of Texas Medical Branch Galveston, Texas 77555;

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原文格式 PDF
正文语种 eng
中图分类生物医学工程;
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2. Measurement of refractive index variation by differential surface plasmon resonance technique [J] . Lee J.-Y., Gu W.-S. Optical review . 2013,第2期

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3. Measurement of Temporal Variation of Refractive Index Distribution with Optical Computed Tomography using Differential Interferometers [J] . Hisao KIKUTA, Koichi IWATA, Takashi NAKANO 日本機械学会論文集. C編 . 1999,第637期

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4. Measurement of Refractive Index Variation of Physiological Analytes using Differential Phase OCT [C] . Kirill V. Larin, Taner Akkin, Thomas E. Milner, Society of Photo-Optical Instrumentation Engineers Conference on Optical Diagnostics and Sensing . 2004

机译：使用差分阶段OCT测量生理分析物的折射率变化
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机译：声学双折射实验测量微分应力

Measurement of Refractive Index Variation of Physiological Analytes using Differential Phase OCT

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