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首页> 外文会议>Conference on Optical Technologies in Biophysics and Medicine IV; Oct 1-4, 2002; Saratov, Russia >Optical Assessment of Tissue Mechanics: Acousto-optical Elastography of Skin
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Optical Assessment of Tissue Mechanics: Acousto-optical Elastography of Skin

机译：组织力学的光学评估：皮肤声光弹性成像

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摘要

A multiphysics approach, combining acoustics, optics, and mechanics can be used to detect regions of skin with distinct mechanical behavior that may indicate a pathology, such as a cancerous skin lesion. Herein, an acousto - optical approach to evaluating the viscoelastic behavior of superficial skin layers will be presented. The method relies upon inducing low frequency guided surface waves in the skin and detecting these waves by monitoring the shift in the backscattered laser speckle pattern created by illuminating a small region of the skin with coherent light. Artificial lesions in the form of chemical cross-linking and chemical softening were induced in superficial porcine skin layers and detected based upon variations in local mechanical behavior. The lesions affect not only the time-of-flight of the guided surface waves, but also change the relative phase of the acoustic waves as determined optically. The method may be applicable in the study and diagnosis of superficial skin lesions.
机译：结合声学，光学和力学的多物理场方法可用于检测具有明显机械行为的皮肤区域，这些机械行为可能指示病理状况，例如癌性皮肤病变。本文中，将提出一种声光方法来评估表皮层的粘弹性行为。该方法依赖于在皮肤中诱导低频引导的表面波并通过监视通过用相干光照射皮肤的一小部分而产生的反向散射激光散斑图案的偏移来检测这些波。以化学交联和化学软化形式的人工损伤在猪的表皮皮肤层中诱导，并根据局部机械行为的变化进行检测。损伤不仅影响被引导的表面波的飞行时间，而且还改变光学确定的声波的相对相位。该方法可适用于浅表皮肤病变的研究和诊断。

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