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Physical Human Lumen Carotid Reconstruction: Life-Size Models by Rapid Prototyping

机译:物理人腔内颈动脉重建:通过快速原型建立与实物大小一样的模型

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Rapid Prototyping (RP) is a technique used in industry for manufacturing prototypes. Its capability to physically reproduce geometrical complex shapes is getting increasing interest in many fields of medicine. In the field of vascular surgery, replicas of artery lumen have utility in complex cases or when standard imaging is felt to be equivocal. Replicas can also facilitate experimental studies of computational vascular fluid-dynamics permitting in-vitro reproductions of blood flow in living subjects before and after surgery. The Virtual VAscular (VIVA) project at CRS4, developed a system able to process three-dimensional (3D) datasets extracted from a Computer Tomography (CT) apparatus, visualize them, reconstruct the geometry of arteries of specific patients, and simulate blood flow in them. In this paper, the applicability of RP techniques to VIVA's real size replicas of a autoptic carotid vessel lumen is presented and an overview of the RP based system developed is provided. The techniques used in our prototype are discussed and experimental results for the creation of a human carotid lumen replica are analysed. We discuss in detail the pipeline of manufacturing process: 3D geometric reconstruction from segmented points, geometry tessellation, STL (Stereo Lithography format) conversion. Moreover we illustrate some technical details of the specific RP technique used to build the lumen replicas, which is called Fused Deposition Modelling (FDM), the materials used for prototypes, throughput time and costs of the FDM models realized. The system is totally based on open-source software. This enables us to control each step of the pipeline, from data acquisition to STL export file. In this context, we present main sources of error encountered during all manufacturing process stages.
机译:快速原型制作(RP)是工业上用于制造原型的技术。它在物理上复制几何复杂形状的能力在医学的许多领域中越来越受到关注。在血管外科领域,在复杂的情况下或当标准成像被认为是模棱两可时,动脉腔的复制品才有用。复制品还可以促进对计算血管流体动力学的实验研究,从而允许在手术前后在活体中体外复制血流。 CRS4的虚拟血管(VIVA)项目开发了一个系统,该系统能够处理从计算机断层扫描(CT)装置提取的三维(3D)数据集,对其进行可视化,重建特定患者动脉的几何形状,并模拟血流他们。在本文中,提出了RP技术对VIVA的颈动脉内腔的真实大小复制品的适用性,并概述了基于RP的系统。讨论了在我们的原型中使用的技术,并分析了创建人颈内腔复制品的实验结果。我们将详细讨论制造过程的流程:从分割点进行3D几何重建,几何细分,STL(立体光刻格式)转换。此外,我们还说明了用于构建管腔副本的特定RP技术的一些技术细节,称为融合沉积建模(FDM),用于原型的材料,生产时间和FDM模型的成本。该系统完全基于开源软件。这使我们能够控制管道的每个步骤,从数据获取到STL导出文件。在这种情况下,我们介绍了在所有制造过程阶段遇到的主要错误来源。

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