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Design and Fabrication of Solid Phantoms for NIR Water Fraction Studies

机译:近红外水份研究的固体模型的设计与制造

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摘要

Tissue simulating phantoms provide a valuable platform for quantitative evaluation of the performance of diffuse optical devices. In this paper we report the development of a poly(dimethylsiloxane) (PDMS) tissue phantom that mimics the spectral characteristics of tissue water. We have developed these phantoms to mimic different water fractions in tissue for testing new devices within the context of clinical applications such as burn wound triage. Compared to liquid phantoms, PDMS phantoms are easier to transport and use, and have a longer usable life than gelatin based phantoms. The pthalocyanine dye 9606 was used to provide an absorption feature of in the vicinity of 970 nm. Scattering properties were independently determined by adding titanium dioxide powder to obtain reduced scattering coefficients similar to that of tissue in the near infrared. Phantom properties were characterized using the techniques of inverse adding doubling and spatial frequency domain imaging. Results presented here demonstrate that we can fabricate solid phantoms that can be used to simulate different water fractions.
机译:组织模拟体模为定量评估漫射光学设备的性能提供了宝贵的平台。在本文中,我们报告了模仿组织水光谱特征的聚二甲基硅氧烷(PDMS)组织模型的开发。我们已经开发出这些幻像来模拟组织中不同的水含量,以在临床应用(例如烧伤伤口分类)中测试新设备。与液态幻影相比,PDMS幻影比基于明胶的幻影更易于运输和使用,并且使用寿命更长。酞菁染料9606用于提供在970nm附近的吸收特征。通过添加二氧化钛粉末来独立获得散射特性,以获得与近红外组织相似的降低的散射系数。使用反向加倍技术和空间频域成像技术来表征幻影属性。此处呈现的结果表明,我们可以制造可用于模拟不同水含量的实体模型。

著录项

  • 来源
    《Design and quality for biomedical technologies X》|2017年|100560A.1-100560A.6|共6页
  • 会议地点 San Francisco(US)
  • 作者单位

    University of California, Irvine, Beckman Laser Institute and Medical Clinic , 1002 Health Sciences Rd East, Irvine, CA 92617, USA;

    University of California, Irvine, Beckman Laser Institute and Medical Clinic , 1002 Health Sciences Rd East, Irvine, CA 92617, USA;

    University of California, Irvine, Beckman Laser Institute and Medical Clinic , 1002 Health Sciences Rd East, Irvine, CA 92617, USA;

    University of California, Irvine, Beckman Laser Institute and Medical Clinic , 1002 Health Sciences Rd East, Irvine, CA 92617, USA;

    University of California, Irvine, Beckman Laser Institute and Medical Clinic , 1002 Health Sciences Rd East, Irvine, CA 92617, USA;

    University of California, Irvine, Beckman Laser Institute and Medical Clinic , 1002 Health Sciences Rd East, Irvine, CA 92617, USA,Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92617, USA;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    tissue simulating phantoms; diffuse optical spectroscopy; turbid media;

    机译:组织模拟体模;漫射光谱浑浊的介质;

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