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首页> 外文会议>Diffuse Optical Imaging of Tissue; Progress in Biomedical Optics and Imaging; vol.8 no.42; Proceedings of SPIE-The International Society for Optical Engineering; vol.6629 >Determination of the optical properties of anisotropic biological media using isotropic and anisotropic diffusion models
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Determination of the optical properties of anisotropic biological media using isotropic and anisotropic diffusion models

机译：使用各向同性和各向异性扩散模型确定各向异性生物介质的光学性质

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摘要

The anisotropic light propagation in biological tissue is investigated in the steady-state and time domains. Monte Carlo simulations performed for tissue that has anisotropic optical properties show that the steady-state and time-resolved reflectance depends strongly on the measurement direction. We examined the determination of the optical properties using an isotropic diffusion model and found that in the time domain, in contrast to steady-state spatially-resolved reflectance measurements, the obtained absorption coefficient does not depend on the measurement direction and is close to the correct value. We performed measurements of the steady-state and time-resolved reflectance from porcine and bovine tendon which confirmed the theoretical findings. In addition, we compared the results obtained from Monte Carlo simulations with the solutions of the anisotropic diffusion theory for reflectance from semi-infinite media and for transmittance from slabs. In contrast to the literature, we found that the anisotropic diffusion equation is, in general, not a valid approximation to the anisotropic light propagation even in the diffusive regime.
机译：在稳态和时域研究了生物组织中各向异性光的传播。对具有各向异性光学特性的组织进行的蒙特卡洛模拟显示，稳态和时间分辨的反射率在很大程度上取决于测量方向。我们使用各向同性扩散模型检查了光学性质的确定，发现在时域中，与稳态空间分辨反射率测量相反，所获得的吸收系数不依赖于测量方向，并且接近于正确的方向。值。我们对猪和牛腱的稳态和时间分辨反射率进行了测量，这证实了理论发现。另外，我们比较了从蒙特卡罗模拟获得的结果与各向异性扩散理论的解，该解对于半无限介质的反射率和平板的透射率。与文献相反，我们发现，即使在扩散状态下，各向异性扩散方程通常也不是对各向异性光传播的有效近似。

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