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A Comparative Study of the Inter-reader Variability of Breast Percent Density Estimation in Digital Mammography: Potential Effect of Reader's Training and Clinical Experience

机译：数字化乳腺X线摄影中乳房密度百分比估计的读者间变异性的比较研究：读者培训和临床经验的潜在影响

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摘要

The variability of breast percent density (PD%) estimation from digital mammography (DM) images was evaluated using measurements from readers with different training and clinical experience. Post-processed DM images (PremiumView~(TM), GE Healthcare) from 40 women were analyzed. Breast PD% estimation was performed using the Cumulus software (Ver. 4.0, Univ. Toronto). Two groups of readers were considered, one with clinical (i.e., radiologists) and one with non-clinical training (i.e., physicists). Consistency of PD% was analyzed using the Pearson correlation coefficient (r) and ANOVA. Inter-reader agreement was higher among clinical (r=0.91, β<0.001), than non-clinical readers (r=0.83, β<0.001). Intra-reader consistency after repeated reads was on average equally high for both groups (r=0.91, p<0.001). Our results suggest that the reader's experience and training has an effect on the obtained PD% measures. The higher correlation among the clinically trained readers could be attributed to their extensive exposure to post-processed DM images and their knowledge of breast anatomy.
机译：使用来自具有不同培训和临床经验的读者的测量值，评估了根据数字乳房X线照片（DM）图像估算的乳房百分比密度（PD％）的变异性。分析了来自40位女性的后处理DM图像（PremiumViewTM，GE Healthcare）。使用Cumulus软件（4.0版，多伦多大学）进行乳房PD％估计。考虑了两组读者，一组具有临床知识（即放射科医生），另一组具有非临床训练（即物理学家）。使用Pearson相关系数（r）和ANOVA分析PD％的一致性。临床之间的读者间一致性较高（r = 0.91，β<0.001），高于非临床读者（r = 0.83，β<0.001）。两组重复阅读后的阅读器内部一致性平均都很高（r = 0.91，p <0.001）。我们的结果表明，读者的经验和培训对所获得的PD％测度有影响。经过临床培训的读者之间的较高相关性可以归因于他们广泛接触后处理的DM图像以及他们对乳房解剖学的了解。

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  • 来源
    《Digital mammography》|2010年|p.114-120|共7页
  • 会议地点 Girona(ES);Girona(ES)
  • 作者

    Emily F. Conant; Diane Li; Sara Gavenonis; Predrag R. Bakic; Ann-Katherine Carton; Cuiping Zhang; Andrew D.A. Maidment; Despina Kontos;

  • 作者单位

    Hospital of the University of Pennsylvania, Breast Imaging Division, 1 Silverstein Building HUP, 3400 Spruce St., Philadelphia PA 19104-4206;

    Hospital of the University of Pennsylvania, Breast Imaging Division, 1 Silverstein Building HUP, 3400 Spruce St., Philadelphia PA 19104-4206;

    Hospital of the University of Pennsylvania, Breast Imaging Division, 1 Silverstein Building HUP, 3400 Spruce St., Philadelphia PA 19104-4206;

    University of Pennsylvania, Department of Radiology, Physics Section, 1 Silverstein Building HUP, 3400 Spruce St., Philadelphia PA 19104-4206;

    University of Pennsylvania, Department of Radiology, Physics Section, 1 Silverstein Building HUP, 3400 Spruce St., Philadelphia PA 19104-4206;

    University of Pennsylvania, Department of Radiology, Physics Section, 1 Silverstein Building HUP, 3400 Spruce St., Philadelphia PA 19104-4206;

    University of Pennsylvania, Department of Radiology, Physics Section, 1 Silverstein Building HUP, 3400 Spruce St., Philadelphia PA 19104-4206;

    Hospital of the University of Pennsylvania, Breast Imaging Division, 1 Silverstein Building HUP, 3400 Spruce St., Philadelphia PA 19104-4206;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物医学工程;
  • 关键词

    digital mammography; breast percent density; breast cancer risk estimation;

    机译：数字乳腺摄影乳房百分比密度；乳腺癌风险评估;

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