• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>DNA computing and molecular programming >Towards Domain-Based Sequence Design for DNA Strand Displacement Reactions
【24h】

Towards Domain-Based Sequence Design for DNA Strand Displacement Reactions

机译：迈向基于域的DNA链置换反应序列设计

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

DNA strand displacement has been used to construct a variety of components, devices, and circuits. The sequences of involved nucleic acid molecules can greatly influence the kinetics and function of strand displacement reactions. To facilitate consideration of spurious reactions during the design process, one common strategy is to subdivide DNA strands into domains, continuous nucleic acid bases that can be abstracted to act as a unit in hybridization and dissociation. Here, considerations for domain-based sequence design are discussed, and heuristics are presented for the sequence design of domains. Based on these heuristics, a randomized algorithm is implemented for sequence design.
机译：DNA链置换已被用于构建各种组件，设备和电路。涉及的核酸分子的序列可以极大地影响链置换反应的动力学和功能。为了便于在设计过程中考虑虚假反应，一种常见的策略是将DNA链细分为域，连续的核酸碱基，可以提取这些核酸碱基以充当杂交和解离的单元。在这里，讨论了基于域的序列设计的考虑，并提出了域序列设计的启发式方法。基于这些启发式方法，实现了用于序列设计的随机算法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号