Synthesis and Characterization of Poly(L-lysine-co-L-aspartic acid)

机译：聚（L-赖氨酸-co-L-天冬氨酸）的合成与表征

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Poly(OBzl-L-aspartate-co-Z-L-lysine) was prepared through ring-opening polymerization. The composition of copolymers could be well controlled by adjusting the feed ratio of (Lys(Z)-NCA to Asp(OBzl)-NCA. 86.1% benzyloxycarbonyl groups on the copolymer chain were deprotected after 2h treatment in HBr/AcOH and HBr/AcOH is nonselective with respect to the two kinds of benzyloxycarbonyl groups on the copolymer. The copolymer has pendant amino and carboxyl groups, so that it could be used to couple drugs, antibodies et al. in terms of tissue engineering and regeneration.

机译：通过开环聚合制备聚（OBzl-L-天冬氨酸-co-Z-L-赖氨酸）。调节（Lys（Z）-NCA与Asp（OBzl）-NCA的进料比可以很好地控制共聚物的组成。在HBr / AcOH和HBr / AcOH中处理2h后，共聚物链上的86.1％苄氧基羰基被脱保护对于共聚物上的两种苄氧羰基基团是非选择性的，该共聚物具有氨基和羧基侧基，因此可用于在组织工程和再生方面偶联药物，抗体等。

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来源
《East-Asian Polymer Conference; 20060528-31; Tianjin(CN)》|2006年|P.338-339|共2页
会议地点 Tianjin(CN)
作者
HU Yuanjun; GONG Feirong; ZHAO Yanchao; CHENG Shuiun;
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Institute of Material Science, East China University of Science and Technology, Shanghai 200237, China;

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正文语种 eng
中图分类复合材料;
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Synthesis and Characterization of Poly(L-lysine-co-L-aspartic acid)

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