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首页> 外文会议>Electrochemistry in medicine and biomedical applications >Combined Chitosan Nano-Bead with Microfluidic-Microelectric Traps of Lead (II) Chelation in Continuous Bloodstream Flow
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Combined Chitosan Nano-Bead with Microfluidic-Microelectric Traps of Lead (II) Chelation in Continuous Bloodstream Flow

机译：壳聚糖纳米珠与微流控微捕集铅（II）螯合的连续血流

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摘要

The selective sorting of Pb~(2+) ions in bloodstream flow has been carried out via mixed chitosan nano-beads aqua-solution and then selectively sponge up the Pb~(2+) ions by a chelating mechanism. To obtain an efficient chelating reaction and a chelating nanobead that can be attracted and separated from the bloodstream flow, a microfluidic component of a microchannel with electrodes has been designed and fabricated by micro-electromechanical process. A local dielectrophoretic force obtained from nonuniform electric fields was elected to manipulate the chelating nanobeads in a continuous bloodstream flow. The experimental studies indicate that the chelating nanobeads undergoes positive dielectrophoresis when suspended in a continuous flow (Re=5.0) and exposed to RF/AC fields at 13.56 MHz frequency. Through this device, the microchannel with electrodes provides a local dielectrophrosis field which is strong enough to manipulate and separate the chelating nanobeads in a continuous bloodstream flow.
机译：通过混合壳聚糖纳米珠水溶液对血流中的Pb〜（2+）离子进行选择性分选，然后通过螯合机理选择性地海绵化Pb〜（2+）离子。为了获得有效的螯合反应和可以被吸引并与血流分离的螯合纳米珠，已经通过微机电方法设计和制造了具有电极的微通道的微流体组件。选择从不均匀电场获得的局部介电泳力来操纵连续血液流中的螯合纳米珠。实验研究表明，螯合纳米珠悬浮在连续流（Re = 5.0）中并暴露于13.56 MHz频率的RF / AC场时会经历正介电电泳。通过该装置，具有电极的微通道提供了局部介电肾小球电场，该电场足够强，可以在连续的血流中操纵和分离螯合的纳米珠。

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