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首页> 外文会议>International Symposium on Flow Visualization >MICROFLUIDIC-MICROELECTRIC TRAPS OF LEAD (II) POLLUTED ERYTHROCYTES IN CONTINUOUS BLOODSTREAM FLOW
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MICROFLUIDIC-MICROELECTRIC TRAPS OF LEAD (II) POLLUTED ERYTHROCYTES IN CONTINUOUS BLOODSTREAM FLOW

机译：铅（II）铅（II）的微细电流阱在连续血流流动中污染的红细胞

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摘要

In order to make possible the selective sorting of lead (II) pollutes erythrocytes cells in a whole blood flow, the first step is to use a sheath flow chamber to focus the blood cells line up in a micro channel. Later, the resulting lead (II) pollutes erythrocytes cells are trapped and separated from the bloodstream by applying other technologies. Creating the polluted erythrocytes make this subsequent separation possible. To effect the actual separation, a micro channel with multiple electric strips has been designed on a silicon substrate and fabricated with micro-electro-mechanical system technology. The erythrocytes cells can be observed via upconversion fluorescence imaging. A local dielectrophoretic (DEP) force, obtained from nonuniform electric fields, was used for manipulating and trapping the polluted erythrocytes in a continuous flow. The experimental studies show that the compounds incur a local dielectrophoretic field when they are suspended in a continuous flow (Re=5.0) and exposed to AC fields at 200 kHz frequency. Using this device, the strip electrodes provide a local dielectrophoretic field strong enough to manipulate and attract nearby polluted erythrocytes in a continuous biological flow.
机译：为了使铅（II）的选择性分选污染整个血流中的污染红细胞细胞，第一步是使用鞘流腔室聚焦在微通道中的血液细胞。后来，通过应用其他技术将所得铅（II）污染污染红细胞细胞从血液中捕获并分离。产生污染的红细胞使随后的分离成为可能。为了实现实际的分离，在硅衬底上设计了具有多个电带的微通道，并用微电机械技术制造。可以通过上转换荧光成像观察红细胞细胞。从非均匀电场获得的局部介电泳（DEP）力用于操纵和捕获连续流动的污染的红细胞。实验研究表明，当它们在连续流动（RE = 5.0）中悬浮并以200kHz频率暴露于AC场时，化合物会产生局部介电泳场。使用该装置，条带电极提供足够强的局部介电泳场，以在连续的生物流动中操纵和吸引附近污染的红细胞。

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