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首页> 外文会议>First International Workshop on the Application of High Intensity Focused Ultrasound (Hifu) in Medicine, May 10-12, 2001, Chongqing, China >Lesion Formation and Visualization Using Dual-Mode HIFU Phased Arrays
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Lesion Formation and Visualization Using Dual-Mode HIFU Phased Arrays

机译：病变形成和可视化使用双模式HIFU相控阵

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摘要

A spherical-section 64-element linear piezocomposite phased array and a supporting driving and data acquisition system were recently tested for use as a dual-mode HIFU applicator system. In therapeutic mode, the array was shown to be capable of producing focal intensities in excess of 3500 W/cm2 at its geometric center (100 mm radius of curvature). In the imaging mode, the array was shown to produce images with dynamic range of 50 dB or better in an elliptical region with 70 and 40 mm axes in the axial and lateral directions, respectively, with respect to its geometric center. These tests confirmed that the array has an imaging field of view (IxFOV) that is larger than its therapeutic operating field (ThxOF). This was confirmed by a series of experimental imaging tests using wire and tissue-mimicking phantoms as well as tissue media. Recently, we have tested the array imaging capability in the visualization of the formation of discrete lesions in freshly excised porcine liver samples. Images were taken before and after discrete lesion formation at various levels of intensity and exposure duration. The experimental results clearly demonstrate the feasibility of lesion visualization with the therapy array, both in terms of spatial and contrast resolution of the formed lesions. It was also found that the use of 2nd Harmonic imaging significantly improves the contrast resolution of the lesions. The feasibility of high-power dual-mode arrays for HIFU lesion formation and visualization offers hope for a most powerful paradigm for image-guided surgery with HIFU arrays.
机译：球形截面的64元素线性压电复合相控阵以及配套的驱动和数据采集系统最近经过测试，可用作双模HIFU喷枪系统。在治疗模式下，该阵列显示出能够在其几何中心（曲率半径为100 mm）产生超过3500 W / cm2的焦点强度。在成像模式下，显示阵列在其几何中心分别在轴向和横向分别具有70和40 mm轴的椭圆区域中产生动态范围为50 dB或更好的图像。这些测试证实了该阵列的成像视野（IxFOV）大于其治疗性手术视野（ThxOF）。通过使用导线和模仿组织的幻像以及组织介质进行的一系列实验成像测试，证实了这一点。最近，我们已经测试了阵列成像的能力，以可视化方式显示新鲜切除的猪肝样品中离散病变的形成。在各种程度的强度和暴露时间下，在离散病变形成之前和之后拍摄图像。实验结果清楚地证明了治疗阵列在病变可视化方面的可行性，无论是在形成的病变的空间分辨率还是对比分辨率上。还发现使用第二谐波成像显着提高了病变的对比度分辨率。大功率双模阵列用于HIFU病变形成和可视化的可行性，为使用HIFU阵列进行图像引导手术的最强大范例提供了希望。

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