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首页> 外文会议>Frontiers in ultrafast optics: biomedical, scientific, and industrial applications XVII >Picosecond laser ablation of polyamide electrospun nanofibers
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Picosecond laser ablation of polyamide electrospun nanofibers

机译：皮秒级激光烧蚀聚酰胺电纺纳米纤维

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摘要

Electrospun nanofibers mats have a great potential in tissue engineering and regenerative medicine. Their high porosity and enormous volume to surface ratio stimulate the growth and adhesion of mammalian cells and serve as a stable support structure. These suitable properties can be further optimized by structuring of the nanofibers. Ultrashort pulsed lasers can be used for modifying of the electrospun nanofibers without significant heat exposure. It seems also possible to generate very fine cuts from the fiber mats. In this study, polyamide electrospun nanofibers samples were processed with picosecond UV-laser irradiation (λ = 355 nm, τ = 15 ps). The samples were processed in dry, wet and immersed condition. To optimize cutting and structuring of nanofiber tissue flakes, the influence of different laser parameters on line widths, edge quality, heat-affected zone (HAZ) and the contamination of the fibers by ablated particles (debris) were examined. One additional aim was the minimization of the flake size. It was possible to generate nanofiber flakes in the sub-millimeter range. The quality of the nanofiber flakes could be improved by ablation near the ablation threshold of the material. For cutting under wet conditions shrinking of the flakes has to be taken into account.
机译：电纺纳米纤维垫在组织工程和再生医学中具有巨大潜力。它们的高孔隙率和巨大的体积与表面积之比刺激了哺乳动物细胞的生长和粘附，并充当了稳定的支撑结构。这些合适的性质可以通过纳米纤维的结构进一步优化。超短脉冲激光器可用于电纺纳米纤维的改性，而不会产生明显的热暴露。似乎也可以从纤维垫上产生非常细的切口。在这项研究中，聚酰胺电纺纳米纤维样品经过皮秒紫外激光辐照处理（λ= 355 nm，τ= 15 ps）。样品在干燥，潮湿和浸没的条件下进行处理。为了优化纳米纤维组织薄片的切割和结构化，研究了不同激光参数对线宽，边缘质量，热影响区（HAZ）以及烧蚀颗粒（碎屑）对纤维的污染的影响。另一个目的是使薄片尺寸最小化。有可能产生亚毫米范围内的纳米纤维薄片。可以通过在材料的烧蚀阈值附近进行烧蚀来改善纳米纤维薄片的质量。为了在潮湿条件下进行切割，必须考虑薄片的收缩。

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