VISUALIZATION OF INDUCED VARIATIONS AT DNA AND CHROMOSOME LEVELS

机译：可视化DNA和染色体水平上的诱导变异

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Current status of visualization methods for DNA and chromosomes is reviewed in relation to mutation genetics and breeding. Now it is quite practical to paint each chromosome in different color by different constitution of repetitive sequences in each chromosome using M-FISH method. It allows easy, reliable and objective detection of chromosome aberration. It is also feasible to detect even single nucleotide changes and double strand breakage visually. All these technological developments provide us more efficient and powerful tools for mutation research.

机译：DNA和染色体的可视化方法的现状与突变遗传学和育种有关。现在，使用M-FISH方法通过在每个染色体中重复序列的不同构成将每个染色体涂成不同的颜色是非常实用的。它可以轻松，可靠和客观地检测染色体畸变。视觉上甚至检测单核苷酸变化和双链断裂也是可行的。所有这些技术发展为我们提供了更有效，更强大的突变研究工具。

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《Gamma Field Symposia no.40; Symposium on Mutation Breeding; History and New Development; 20010711-12; Ohmiya-machi, Naka-gun(JP)》|2001年|P.21-28|共8页
会议地点 Ohmiya-machi Naka-gun(JP)
作者
Kiichi FUKUI;
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作者单位

Department of Biotechnology, Graduate School of Engineering, Osaka University Yamadaoka 2-1, Suita-shi, Osaka-fu, 565-0871;

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原文格式 PDF
正文语种 eng
中图分类 S335.21;
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3. Influence of glutathione levels on radiation-induced chromosomal DNA damage and repair in human peripheral lymphocytes. [J] . Pujari G, Berni A, Palitti F Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2009,第1a2期

机译：谷胱甘肽水平对辐射诱导的染色体DNA损伤和人类外周淋巴细胞修复的影响。
4. VISUALIZATION OF INDUCED VARIATIONS AT DNA AND CHROMOSOME LEVELS [C] . Kiichi FUKUI, Gamma Field Symposia no.40 Symposium on Mutation Breeding; History and New Development . 2003

机译：DNA和染色体水平诱导变化的可视化
5. Comparison of the types and levels of genotoxin-induced chromosomal abnormalities in cultured human cells. [D] . Hernandez-Martinez, Raymundo. 1996

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6. Tissue-specific variation in DNA methylation levels along human chromosome 1 [O] . Cecilia De Bustos, Edward Ramos, Janet M Young, 2009

机译：沿人类1号染色体的DNA甲基化水平的组织特异性变异
7. Chromosomal Translocations in Yeast Induced by Low Levels of DNA Polymerase A Model for Chromosome Fragile Sites [O] . Lemoine Francene J., Degtyareva Natasha P., Lobachev Kirill, 2005

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8. Interpretation of heavy ion effects. - Comparison of chromosomal damage induced by low and high LET radiation. - Calculation of RBE for endpoints in vitro and in vivo based on charged particle track structure. - Delayed chromosomal instability induced by high and low LET radiation. - Influence of radiation quality on strand breaks in viral and cellular DNA [R] . Kraft, G. , Scholz, M. , Nasonova, E. , 1995

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VISUALIZATION OF INDUCED VARIATIONS AT DNA AND CHROMOSOME LEVELS

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