首页> 外文会议>High-Power Laser Ablation VI pt.1 >In vivo manipulation of biological systems with femtosecond laser pulses
【24h】

In vivo manipulation of biological systems with femtosecond laser pulses

机译:飞秒激光脉冲在体内操纵生物系统

获取原文
获取原文并翻译 | 示例

摘要

Femtosecond laser pulses have the unique ability to deposit energy into a microscopic volume in the bulk of a material that is transparent to the laser wavelength without affecting the surface of the material. Here we review the use of this capability to disrupt specifically targeted structures in live cells and animals with the goal of elucidating function and modeling disease states. Particular attention will be paid to recent work that uses femtosecond laser disruption to injure cerebral blood vessels that lie below the brain surface in a live, anesthetized rat. By varying the degree of injury, the vessel can be made to leak blood plasma, to rupture, or to clot. This technique thus provides a versatile model of cerebrovascular disorders such as small-scale stroke.
机译:飞秒激光脉冲具有独特的能力,可以将能量沉积到对激光波长透明的大部分材料中的微观体积内,而不会影响材料的表面。在这里,我们综述了利用这种功能破坏活细胞和动物中特定靶向的结构,以阐明功能和模拟疾病状态的目的。将特别关注使用飞秒激光打断来伤害活着的麻醉大鼠大脑表面以下的脑血管的最新工作。通过改变损伤程度,可以使血管渗漏血浆,破裂或凝结。因此,该技术提供了脑血管疾病(例如小规模卒中)的通用模型。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号